Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.38 |
| ▸ | POLB | P06746 | 2/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | CCR1 | P32246 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 3/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | RECQL | P46063 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 2/20 | 0.35 |
| ▸ | RAB9A | P51151 | 2/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11130545 | 0.84 | MAPT (0.33) | SMN1; SMN2POLBKMT2AMEN1CCR1 | |
| SCHEMBL31081858 | 0.83 | ALDH1A1 (0.36) | SMN1; SMN2POLBHTTKMT2AMEN1 | |
| SCHEMBL8325428 | 0.80 | MAPT (0.36) | SMN1; SMN2KMT2AMEN1CCR1MAPT | |
| SCHEMBL16832615 | 0.78 | LMNA (0.51) | SMN1; SMN2POLBKMT2ALMNAALDH1A1 | |
| SCHEMBL16833019 | 0.77 | SLC2A1 (0.48) | MAPT | |
| SCHEMBL16832544 | 0.76 | CYP1A2 (0.37) | SMN1; SMN2LMNAALDH1A1 | |
| SCHEMBL18320582 | 0.76 | CYP1A2 (0.41) | SMN1; SMN2KMT2AMEN1LMNAALDH1A1 | |
| SCHEMBL16832211 | 0.75 | TDP1 (0.39) | SMN1; SMN2HTTKMT2AMEN1CCR1 | |
| SCHEMBL16832143 | 0.75 | RAB9A (0.56) | SMN1; SMN2HTTKMT2AMEN1CCR1 | |
| SCHEMBL16832854 | 0.75 | ALDH1A1 (0.43) | SMN1; SMN2HTTCCR1LMNAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0789698-B1 | N-(1-ETHYL-4-PYRAZOLYL)TRIAZOLOAZINESULFONAMIDE HERBICIDES | DOW AGROSCIENCES LLC (US) | 1999-07-07 | — | — | EP | disclosed |
| US-5763359-A | N-(1-ethyl-4-pyrazolyl)triazoloazinesulfonamide herbicides | DOW AGROSCIENCES LLC (US) | 1998-06-09 | — | — | US | disclosed |
| EP-0789698-A1 | N-(1-ETHYL-4-PYRAZOLYL)TRIAZOLOAZINESULFONAMIDE HERBICIDES | DOWELANCO (US) | 1997-08-20 | — | — | EP | disclosed |
| WO-1997008172-A1 | N-(1-ETHYL-4-PYRAZOLYL)TRIAZOLOAZINESULFONAMIDE HERBICIDES | DOWELANCO (US) | 1997-03-06 | — | — | WO | disclosed |