Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.30 |
| ▸ | CCR1 | P32246 | 1/20 | 0.30 |
| ▸ | PKM | P14618 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11130545 | 0.80 | MAPT (0.33) | MAPTMEN1KMT2ANPSR1SMN1; SMN2 | |
| SCHEMBL8324291 | 0.80 | SMN1; SMN2 (0.38) | MAPTMEN1KMT2ANPSR1NPC1 | |
| SCHEMBL31081858 | 0.79 | ALDH1A1 (0.36) | MAPTMEN1KMT2ANPSR1HPGD | |
| SCHEMBL8325471 | 0.73 | HPGD (0.33) | HPGD | |
| SCHEMBL8803385 | 0.68 | — | — | |
| SCHEMBL5278824 | 0.66 | ALDH1A1 (0.35) | NPC1ALDH1A1 | |
| SCHEMBL16832375 | 0.66 | RAB9A (0.42) | MAPTMEN1KMT2ANPSR1NPC1 | |
| SCHEMBL16833034 | 0.64 | DCTPP1 (0.41) | MAPT | |
| SCHEMBL8962070 | 0.64 | PTGS1 (0.40) | MAPTMEN1KMT2ASMN1; SMN2ALDH1A1 | |
| SCHEMBL8952165 | 0.64 | PKM (0.46) | MAPTNPSR1NPC1SMN1; SMN2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0789698-B1 | N-(1-ETHYL-4-PYRAZOLYL)TRIAZOLOAZINESULFONAMIDE HERBICIDES | DOW AGROSCIENCES LLC (US) | 1999-07-07 | — | — | EP | disclosed |
| US-5763359-A | N-(1-ethyl-4-pyrazolyl)triazoloazinesulfonamide herbicides | DOW AGROSCIENCES LLC (US) | 1998-06-09 | — | — | US | disclosed |
| EP-0789698-A1 | N-(1-ETHYL-4-PYRAZOLYL)TRIAZOLOAZINESULFONAMIDE HERBICIDES | DOWELANCO (US) | 1997-08-20 | — | — | EP | disclosed |
| WO-1997008172-A1 | N-(1-ETHYL-4-PYRAZOLYL)TRIAZOLOAZINESULFONAMIDE HERBICIDES | DOWELANCO (US) | 1997-03-06 | — | — | WO | disclosed |