Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
| ▸ | GABRA2 | P47869 | 9/20 | 0.35 |
| ▸ | GABRB2 | P47870 | 9/20 | 0.35 |
| ▸ | CDC7 | O00311 | 1/20 | 0.35 |
| ▸ | CDK2 | P24941 | 1/20 | 0.35 |
| ▸ | GABRB3 | P28472 | 7/20 | 0.34 |
| ▸ | GABRP | O00591 | 3/20 | 0.34 |
| ▸ | GABRD | O14764 | 3/20 | 0.34 |
| ▸ | GABRA1 | P14867 | 3/20 | 0.34 |
| ▸ | GABRB1 | P18505 | 3/20 | 0.34 |
| ▸ | GABRG2 | P18507 | 3/20 | 0.34 |
| ▸ | GABRA5 | P31644 | 3/20 | 0.34 |
| ▸ | GABRA3 | P34903 | 3/20 | 0.34 |
| ▸ | GABRA4 | P48169 | 3/20 | 0.34 |
| ▸ | GABRE | P78334 | 3/20 | 0.34 |
| ▸ | GABRA6 | Q16445 | 3/20 | 0.34 |
| ▸ | GABRG1 | Q8N1C3 | 3/20 | 0.34 |
| ▸ | GABRG3 | Q99928 | 3/20 | 0.34 |
| ▸ | GABRQ | Q9UN88 | 3/20 | 0.34 |
| ▸ | RPS6KA5 | O75582 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8320585 | 0.84 | CDC7 (0.39) | RECQLCDC7CDK2RPS6KA5ALDH1A1 | |
| SCHEMBL8322859 | 0.83 | RORC (0.39) | GABRA2GABRB2GABRB3GABRPGABRD | |
| SCHEMBL8323616 | 0.83 | GABRA2 (0.40) | GABRA2GABRB2CDC7CDK2GABRB3 | |
| SCHEMBL8324428 | 0.83 | RECQL (0.51) | RECQLALDH1A1MAPTHPGDTDP1 | |
| SCHEMBL18372284 | 0.71 | FGFR1 (0.39) | MAPT | |
| SCHEMBL2827266 | 0.71 | BIRC5 (0.50) | GABRA2GABRB2CDC7CDK2GABRB3 | |
| SCHEMBL8666855 | 0.70 | TDP1 (0.44) | ALDH1A1MAPTHPGDTDP1 | |
| SCHEMBL8324003 | 0.69 | CDC7 (0.36) | GABRA2GABRB2CDC7CDK2GABRB3 | |
| SCHEMBL8319454 | 0.69 | MAT2A (0.42) | CDC7CDK2ALDH1A1MAPTHPGD | |
| SCHEMBL6867874 | 0.69 | CDC7 (0.42) | RECQLGABRA2GABRB2CDC7CDK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0729470-B1 | HERBICIDAL PYRROLOPYRIDINE COMPOUNDS | ZENECA LTD (GB) | 1999-05-12 | — | — | EP | claimed |
| US-5451566-A | PREEMERGENCE AND POSTEMERGENCE HERBICIDES | ZENECA LIMITED (GB) | 1995-09-19 | — | — | US | claimed |
| WO-1995014019-A1 | HERBICIDAL PYRROLOPYRIDINE COMPOUNDS | ZENECA LIMITED (GB) | 1995-05-26 | — | — | WO | claimed |
| EP-0729470-B1 | HERBICIDAL PYRROLOPYRIDINE COMPOUNDS | ZENECA LTD (GB) | 1999-05-12 | — | — | EP | disclosed |
| US-5451566-A | PREEMERGENCE AND POSTEMERGENCE HERBICIDES | ZENECA LIMITED (GB) | 1995-09-19 | — | — | US | disclosed |
| WO-1995014019-A1 | HERBICIDAL PYRROLOPYRIDINE COMPOUNDS | ZENECA LIMITED (GB) | 1995-05-26 | — | — | WO | disclosed |