Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 1/20 | 0.41 |
| ▸ | CDK8 | P49336 | 1/20 | 0.37 |
| ▸ | CLK1 | P49759 | 1/20 | 0.35 |
| ▸ | CHEK1 | O14757 | 2/20 | 0.34 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.34 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.33 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.33 |
| ▸ | GRIN2B | Q13224 | 5/20 | 0.32 |
| ▸ | BRD4 | O60885 | 1/20 | 0.32 |
| ▸ | GAK | O14976 | 1/20 | 0.31 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.31 |
| ▸ | ALK | Q9UM73 | 1/20 | 0.31 |
| ▸ | FYN | P06241 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18902075 | 0.78 | BRD4 (0.34) | BRD4CYP1A2 | |
| SCHEMBL18902127 | 0.77 | JAK2 (0.35) | KDM4EALDH1A1HPGD | |
| SCHEMBL8324146 | 0.77 | SCN9A (0.36) | CLK1GRIN2BBRD4 | |
| SCHEMBL8321214 | 0.73 | BRD4 (0.59) | MAOBCDK8CLK1CHEK1EGLN1 | |
| Hydrochloric Acid SCHEMBL7393103 | 0.65 | HTR1D (0.47) | CHEK1CDK2 | |
| SCHEMBL12829859 | 0.63 | CDK8 (0.60) | CDK8CLK1CHEK1PDGFRBPDGFRA | |
| SCHEMBL18098819 | 0.63 | DYRK1A (0.37) | CDK2 | |
| SCHEMBL13620692 | 0.61 | CHEK1 (0.50) | MAOBCDK8CLK1CHEK1EGLN1 | |
| SCHEMBL19366587 | 0.61 | SRC (0.40) | CHEK1MEN1ALDH1A1MAPTKMT2A | |
| SCHEMBL16532869 | 0.61 | PDGFRB (0.59) | CLK1CHEK1PDGFRBPDGFRAGRIN2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004078756-A2 | JNK INHIBITORS | EISAI CO., LTD. (JP) | 2004-09-16 | — | — | WO | disclosed |