Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.41 |
| ▸ | KDR | P35968 | 3/20 | 0.40 |
| ▸ | SRC | P12931 | 2/20 | 0.40 |
| ▸ | ABL1 | P00519 | 1/20 | 0.40 |
| ▸ | EGFR | P00533 | 1/20 | 0.40 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.40 |
| ▸ | KIT | P10721 | 1/20 | 0.40 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.40 |
| ▸ | BRAF | P15056 | 1/20 | 0.40 |
| ▸ | EPHB4 | P54760 | 1/20 | 0.40 |
| ▸ | TEK | Q02763 | 1/20 | 0.40 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.40 |
| ▸ | CDK4 | P11802 | 2/20 | 0.39 |
| ▸ | CCND1 | P24385 | 2/20 | 0.39 |
| ▸ | CCND2 | P30279 | 2/20 | 0.39 |
| ▸ | CCND3 | P30281 | 2/20 | 0.39 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.39 |
| ▸ | ESR1 | P03372 | 2/20 | 0.39 |
| ▸ | LCK | P06239 | 3/20 | 0.38 |
| ▸ | WEE1 | P30291 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8330060 | 0.90 | MAPT (0.39) | LMNAKDM4EPOLBMAPTOPRM1 | |
| SCHEMBL8328970 | 0.87 | PDE4B (0.40) | HDAC6KDM4EPOLBMAPTOPRM1 | |
| SCHEMBL8327531 | 0.84 | MAPT (0.43) | HRH3KDRSRCABL1EGFR | |
| Hydrochloric Acid SCHEMBL9050309 | 0.83 | MAPT (0.42) | HRH3KDRSRCABL1EGFR | |
| SCHEMBL8331716 | 0.83 | MAPT (0.37) | CDK4LMNAKDM4EPOLBMAPT | |
| SCHEMBL8328444 | 0.83 | MAPT (0.42) | HDAC6KDM4EPOLBMAPTOPRM1 | |
| SCHEMBL8324676 | 0.81 | P2RX3 (0.41) | SCN2AKDM4EPOLBMAPTOPRM1 | |
| SCHEMBL8329541 | 0.80 | HDAC1 (0.43) | KDRHDAC6POLBMAPTRAD52 | |
| SCHEMBL8324456 | 0.79 | MAPT (0.55) | LMNAMAPT | |
| Hydrochloric Acid SCHEMBL8328215 | 0.78 | MAPT (0.54) | LMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0705260-B1 | CONDENSED 4-AMINOPYRIDINES WITH ANTIRHEUMATIC ACTIVITY | KNOLL AG (DE) | 1999-03-03 | — | — | EP | claimed |