Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.40 |
| ▸ | LMNA | P02545 | 4/20 | 0.40 |
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
| ▸ | NPC1 | O15118 | 3/20 | 0.40 |
| ▸ | RAB9A | P51151 | 3/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | EGFR | P00533 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | METAP2 | P50579 | 1/20 | 0.37 |
| ▸ | MAOA | P21397 | 1/20 | 0.37 |
| ▸ | MAOB | P27338 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.36 |
| ▸ | F2 | P00734 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8321150 | 0.82 | MGLL (0.39) | ALDH1A1LMNAHTTHPGDMAPT | |
| SCHEMBL8320461 | 0.81 | EGFR (0.52) | ALDH1A1KMT2ASMN1; SMN2LMNAMEN1 | |
| SCHEMBL8324894 | 0.79 | KMT2A (0.50) | ALDH1A1KMT2ASMN1; SMN2LMNAMEN1 | |
| SCHEMBL4258903 | 0.74 | MGLL (0.46) | ALDH1A1KMT2ASMN1; SMN2MEN1NPC1 | |
| SCHEMBL4258906 | 0.74 | MGLL (0.46) | ALDH1A1KMT2ASMN1; SMN2MEN1NPC1 | |
| SCHEMBL1579799 | 0.74 | ALDH1A1 (0.45) | ALDH1A1NPC1RAB9AHPGDMAOB | |
| SCHEMBL28388559 | 0.74 | P4HB (0.47) | ALDH1A1KMT2ASMN1; SMN2LMNAMEN1 | |
| SCHEMBL1579334 | 0.74 | NPSR1 (0.43) | ALDH1A1SMN1; SMN2HPGDKDM4E | |
| SCHEMBL1579332 | 0.74 | NPSR1 (0.43) | ALDH1A1SMN1; SMN2HPGDKDM4E | |
| SCHEMBL8320891 | 0.74 | KMT2A (0.50) | ALDH1A1KMT2ASMN1; SMN2LMNAMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004071401-A2 | HYDROXAMIC ACID DERIVATIVES AS HISTONE DEACETYLASE INHIBITORS (HDCA) | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2004-08-26 | — | — | WO | disclosed |