Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.50 |
| ▸ | MEN1 | O00255 | 3/20 | 0.50 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.49 |
| ▸ | LMNA | P02545 | 5/20 | 0.49 |
| ▸ | GAA | P10253 | 3/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 3/20 | 0.47 |
| ▸ | NPC1 | O15118 | 3/20 | 0.47 |
| ▸ | MAOA | P21397 | 1/20 | 0.47 |
| ▸ | MAOB | P27338 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | EGFR | P00533 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | F2 | P00734 | 1/20 | 0.44 |
| ▸ | F10 | P00742 | 1/20 | 0.44 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8320461 | 0.89 | EGFR (0.52) | KMT2AMEN1TAAR1ALDH1A1LMNA | |
| SCHEMBL8317737 | 0.81 | LMNA (0.55) | KMT2AMEN1ALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL8317750 | 0.81 | ALDH1A1 (0.59) | KMT2AMEN1ALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL28831003 | 0.79 | ALDH1A1 (0.63) | KMT2AMEN1TAAR1ALDH1A1LMNA | |
| SCHEMBL8325102 | 0.79 | ALDH1A1 (0.40) | KMT2AMEN1TAAR1ALDH1A1LMNA | |
| SCHEMBL8321251 | 0.77 | LMNA (0.55) | KMT2AMEN1ALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL8320891 | 0.74 | KMT2A (0.50) | KMT2AMEN1TAAR1ALDH1A1LMNA | |
| SCHEMBL19244362 | 0.74 | KDM4E (0.74) | KMT2AALDH1A1SMN1; SMN2MAOAMAOB | |
| SCHEMBL19244360 | 0.74 | KDM4E (0.74) | KMT2AALDH1A1SMN1; SMN2MAOAMAOB | |
| SCHEMBL8317458 | 0.74 | PKM (0.49) | KMT2AMEN1ALDH1A1LMNAGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004071401-A2 | HYDROXAMIC ACID DERIVATIVES AS HISTONE DEACETYLASE INHIBITORS (HDCA) | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2004-08-26 | — | — | WO | disclosed |