Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SYK | P43405 | 5/20 | 0.38 |
| ▸ | MAPT | P10636 | 7/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.37 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.37 |
| ▸ | RAD52 | P43351 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.36 |
| ▸ | CDC7 | O00311 | 1/20 | 0.36 |
| ▸ | PLK4 | O00444 | 1/20 | 0.36 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.36 |
| ▸ | AURKA | O14965 | 1/20 | 0.36 |
| ▸ | DCLK1 | O15075 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8330039 | 0.84 | MAPT (0.44) | SYKMAPTKDM4EMAPK1CDC7 | |
| SCHEMBL8328465 | 0.83 | PTGS2 (0.40) | MAPTKDM4EKMT2APOLBOPRM1 | |
| SCHEMBL8327888 | 0.83 | MAPT (0.38) | MAPTKMT2APOLBMEN1MTOR | |
| SCHEMBL8323960 | 0.79 | MAPT (0.54) | MAPTKDM4EKMT2AMEN1SLC2A1 | |
| Hydrochloric Acid SCHEMBL8325608 | 0.79 | MAPT (0.53) | MAPTKDM4EKMT2AMEN1SLC2A1 | |
| SCHEMBL8325273 | 0.78 | CSF1R (0.39) | MAPTKMT2ANPSR1MEN1ALDH1A1 | |
| SCHEMBL8330323 | 0.77 | MAPK8 (0.42) | MAPTLMNAMAPK8TP53SMN1; SMN2 | |
| SCHEMBL8325619 | 0.75 | THRB (0.31) | KMT2AMEN1STK3 | |
| SCHEMBL8329432 | 0.73 | MAPT (0.55) | MAPTKMT2AMEN1SLC2A1TP53 | |
| SCHEMBL8326891 | 0.73 | MAPT (0.55) | MAPTKMT2AMEN1SLC2A1TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0705260-B1 | CONDENSED 4-AMINOPYRIDINES WITH ANTIRHEUMATIC ACTIVITY | KNOLL AG (DE) | 1999-03-03 | — | — | EP | claimed |