Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 1/20 | 0.40 |
| ▸ | P2RX3 | P56373 | 15/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.37 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.37 |
| ▸ | RAD52 | P43351 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | DHODH | Q02127 | 1/20 | 0.36 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.36 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8327174 | 0.86 | P2RX3 (0.43) | PTGS2P2RX3 | |
| SCHEMBL8329674 | 0.85 | MAPT (0.43) | PTGS2P2RX3KDM4EPOLBMAPT | |
| SCHEMBL8328091 | 0.83 | SYK (0.38) | KDM4EPOLBMAPTOPRM1OPRD1 | |
| SCHEMBL8327888 | 0.82 | MAPT (0.38) | POLBMAPTKMT2ADHODHPDE10A | |
| SCHEMBL8328461 | 0.81 | MAPT (0.52) | PTGS2MAPT | |
| Hydrochloric Acid SCHEMBL8328640 | 0.80 | MAPT (0.51) | PTGS2KDM4EMAPT | |
| SCHEMBL8330323 | 0.80 | MAPK8 (0.42) | MAPTPDE10A | |
| SCHEMBL8324676 | 0.78 | P2RX3 (0.41) | P2RX3KDM4EPOLBMAPTOPRM1 | |
| SCHEMBL8325406 | 0.77 | PDE10A (0.41) | PTGS2P2RX3KDM4EPOLBMAPT | |
| Hydrochloric Acid SCHEMBL8468831 | 0.75 | PDE10A (0.42) | PTGS2P2RX3KDM4EPOLBMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0705260-B1 | CONDENSED 4-AMINOPYRIDINES WITH ANTIRHEUMATIC ACTIVITY | KNOLL AG (DE) | 1999-03-03 | — | — | EP | claimed |