Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | BLM | P54132 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
| ▸ | GSK3B | P49841 | 9/20 | 0.33 |
| ▸ | DRD4 | P21917 | 1/20 | 0.32 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.32 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.32 |
| ▸ | CCR2 | P41597 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8321742 | 0.90 | PKM (0.37) | KMT2AMEN1ALDH1A1PKMGSK3B | |
| SCHEMBL8328809 | 0.89 | POLB (0.38) | POLBMAPTALDH1A1DRD4TMEM97 | |
| SCHEMBL8328415 | 0.89 | GSK3B (0.36) | POLBKMT2AMEN1GSK3BDRD4 | |
| SCHEMBL8327681 | 0.88 | DRD4 (0.41) | POLBCYP1A2CYP3A4GSK3BDRD4 | |
| SCHEMBL8325382 | 0.83 | DRD4 (0.34) | PKMDRD4 | |
| SCHEMBL8330578 | 0.79 | CYP1A2 (0.36) | POLBMAPTCYP1A2CYP3A4CYP2C9 | |
| SCHEMBL8328371 | 0.77 | NOS3 (0.35) | — | |
| SCHEMBL8327693 | 0.74 | DRD4 (0.41) | ALDH1A1DRD4 | |
| SCHEMBL8326763 | 0.72 | DRD4 (0.41) | ALDH1A1DRD4 | |
| SCHEMBL8325386 | 0.71 | DRD4 (0.40) | CYP1A2CYP3A4CYP2C9DRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0760368-B1 | PYRIMIDINE DERIVATIVES | NISSHIN FLOUR MILLING CO (JP) | 1999-07-28 | — | — | EP | disclosed |
| EP-0760368-A1 | NOVEL PYRIMIDINE DERIVATIVE | NISSHIN FLOUR MILLING CO., LTD. (JP) | 1997-03-05 | — | — | EP | disclosed |