Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2A | P29274 | 1/20 | 0.37 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | KCNJ5 | P48544 | 1/20 | 0.33 |
| ▸ | KCNJ3 | P48549 | 1/20 | 0.33 |
| ▸ | HTR1A | P08908 | 1/20 | 0.33 |
| ▸ | HTR2C | P28335 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.30 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9070284 | 0.74 | HRH4 (0.33) | ALDH1A1KDM4EPOLB | |
| SCHEMBL5709843 | 0.67 | KDM4E (0.39) | ALDH1A1MAPTKDM4ESMN1; SMN2CYP3A4 | |
| SCHEMBL8330832 | 0.67 | ADORA2A (0.38) | ADORA2AADORA1KDM4EKCNJ5KCNJ3 | |
| SCHEMBL4016272 | 0.64 | — | — | |
| SCHEMBL8671760 | 0.64 | TDP1 (0.45) | ADORA2AADORA1ALDH1A1MAPTKDM4E | |
| SCHEMBL18649540 | 0.63 | CYP2A6 (0.38) | ADORA2AADORA1ALDH1A1KDM4ESMN1; SMN2 | |
| SCHEMBL8329276 | 0.62 | ADORA2A (0.35) | ADORA2AADORA1KDM4EKCNJ5KCNJ3 | |
| SCHEMBL1896687 | 0.62 | MAT2A (0.37) | ALDH1A1KDM4ESMN1; SMN2 | |
| SCHEMBL15743183 | 0.62 | MAT2A (0.37) | — | |
| SCHEMBL28045824 | 0.61 | CYP2C9 (0.41) | ADORA2AADORA1ALDH1A1KDM4ESMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016043661-A1 | MODIFIED PEPTIDE NUCLEIC ACIDS AND THEIR USE | NANYANG TECHNOLOGICAL UNIVERSITY (SG) | 2016-03-24 | — | — | WO | disclosed |
| EP-0544210-B1 | Process for the preparation of in position 5 substituted cytosines and of other 4,5-disubstituted pyrimidin-2(1H)-ones, also the forth-issuing intermediates | HOECHST AG (DE) | 1999-11-03 | — | — | EP | disclosed |
| US-5631259-A | PURINE BASE DERIVATIVES FOR NUCLEOSIDES | HOECHST AKTIENGESELLSCHAFT (DE) | 1997-05-20 | — | — | US | disclosed |
| US-5359067-A | Process for the preparation of 5-substituted cytosines and other 4,5-disubstituted pyrimidin-2(1H)-ones, and intermediates arising in the course of this | HOECHST AKTIENGESELLSCHAFT (DE) | 1994-10-25 | — | — | US | disclosed |
| EP-0544210-A1 | Process for the preparation of in position 5 substituted cytosines and of other 4,5-disubstituted pyrimidin-2(1H)-ones, also the forth-issuing intermediates | HOECHST AKTIENGESELLSCHAFT (DE) | 1993-06-02 | — | — | EP | disclosed |
| EP-0521463-A2 | Substituted cyclic cycloalkyltriols, process, intermediates for their preparation and their use as antiviral and antiparasitic agents | HOECHST AKTIENGESELLSCHAFT (DE) | 1993-01-07 | — | — | EP | disclosed |