Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NFE2L2 | Q16236 | 5/20 | 0.55 |
| ▸ | GPR52 | Q9Y2T5 | 1/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | THPO | P40225 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.46 |
| ▸ | GRM5 | P41594 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | BLM | P54132 | 1/20 | 0.46 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.46 |
| ▸ | TAAR1 | Q96RJ0 | 3/20 | 0.44 |
| ▸ | MAOA | P21397 | 1/20 | 0.43 |
| ▸ | MAOB | P27338 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7460344 | 0.90 | TAAR1 (0.53) | NFE2L2GPR52CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL1115608 | 0.82 | MAOB (0.46) | GPR52TAAR1MAOAMAOBALDH1A1 | |
| SCHEMBL7814468 | 0.81 | NFE2L2 (0.48) | NFE2L2GPR52NPC1RAB9ATAAR1 | |
| SCHEMBL8321871 | 0.78 | MAOB (0.60) | CYP3A4NPC1TAAR1MAOAMAOB | |
| SCHEMBL3822095 | 0.78 | GPR52 (0.51) | GPR52NPC1RAB9ATAAR1MAOA | |
| SCHEMBL8324164 | 0.78 | ALDH1A1 (0.51) | NPC1CHRM5RAB9ATAAR1MAOB | |
| SCHEMBL8366338 | 0.77 | NFE2L2 (0.54) | NFE2L2CYP1A2CYP3A4CYP2D6PKM | |
| SCHEMBL8591746 | 0.76 | TAAR1 (0.65) | GPR52TAAR1MAOAMAOBALDH1A1 | |
| SCHEMBL8840811 | 0.76 | NFE2L2 (0.52) | NFE2L2CYP1A2CYP3A4CYP2D6PKM | |
| SCHEMBL154188 | 0.76 | NFE2L2 (0.55) | NFE2L2CYP1A2CYP3A4CYP2D6PKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5885981-A | REACTING A HALOGENATED ALKYL COMPOUND WITH A PENEM COMPOUND | SUNTORY LIMITED (JP) | 1999-03-23 | — | — | US | claimed |
| US-5830889-A | ANTIBIOTIC IN ORAL DOSAGE FORMS | SUNTORY LIMITED (JP) | 1998-11-03 | — | — | US | claimed |
| WO-1992003442-A1 | ANTIBACTERIAL PENEM ESTERS DERIVATIVES | SUNTORY LIMITED (JP) | 1992-03-05 | — | — | WO | claimed |
| EP-0544907-B1 | ANTIBACTERIAL PENEM ESTERS DERIVATIVES | SUNTORY LTD (JP) | 1999-10-27 | — | — | EP | disclosed |
| EP-0948496-A2 | SUBSTITUTED PYRIMIDINONE AND PYRIDONE COMPOUNDS AND METHODS OF USE | Amgen inc. (US) | 1999-10-13 | — | — | EP | disclosed |
| US-5885981-A | REACTING A HALOGENATED ALKYL COMPOUND WITH A PENEM COMPOUND | SUNTORY LIMITED (JP) | 1999-03-23 | — | — | US | disclosed |
| US-5885981-A | REACTING A HALOGENATED ALKYL COMPOUND WITH A PENEM COMPOUND | SUNTORY LIMITED (JP) | 1999-03-23 | — | — | US | disclosed |
| US-5830889-A | ANTIBIOTIC IN ORAL DOSAGE FORMS | SUNTORY LIMITED (JP) | 1998-11-03 | — | — | US | disclosed |
| US-5830889-A | ANTIBIOTIC IN ORAL DOSAGE FORMS | SUNTORY LIMITED (JP) | 1998-11-03 | — | — | US | disclosed |
| WO-1998024780-A2 | SUBSTITUTED PYRIMIDINONE AND PYRIDINONE COMPOUNDS AND THEIR USE | AMGEN INC. (US) | 1998-06-11 | — | — | WO | disclosed |
| EP-0757050-A1 | Antibacterial penem esters derivatives | SUNTORY LIMITED (JP) | 1997-02-05 | — | — | EP | disclosed |
| EP-0544907-A1 | ANTIBACTERIAL PENEM ESTERS DERIVATIVES | SUNTORY LIMITED (JP) | 1993-06-09 | — | — | EP | disclosed |
| WO-1992003442-A1 | ANTIBACTERIAL PENEM ESTERS DERIVATIVES | SUNTORY LIMITED (JP) | 1992-03-05 | — | — | WO | disclosed |
| WO-1992003442-A1 | ANTIBACTERIAL PENEM ESTERS DERIVATIVES | SUNTORY LIMITED (JP) | 1992-03-05 | — | — | WO | disclosed |