Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.50 |
| ▸ | RECQL | P46063 | 1/20 | 0.50 |
| ▸ | MLKL | Q8NB16 | 2/20 | 0.49 |
| ▸ | NPC1 | O15118 | 2/20 | 0.47 |
| ▸ | RAB9A | P51151 | 2/20 | 0.47 |
| ▸ | STAT1 | P42224 | 1/20 | 0.45 |
| ▸ | IDO1 | P14902 | 1/20 | 0.44 |
| ▸ | MGAM | O43451 | 1/20 | 0.44 |
| ▸ | HDAC3 | O15379 | 3/20 | 0.44 |
| ▸ | HDAC4 | P56524 | 3/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8325032 | 1.00 | SMN1; SMN2 (0.50) | SMN1; SMN2KMT2AMAPTNPSR1KDM4E | |
| SCHEMBL8325372 | 0.88 | HDAC1 (0.58) | SMN1; SMN2KMT2AMAPTNPSR1MEN1 | |
| SCHEMBL8319266 | 0.84 | SMN1; SMN2 (0.50) | SMN1; SMN2KMT2AMAPTNPSR1KDM4E | |
| SCHEMBL16756501 | 0.80 | ALPL (0.58) | SMN1; SMN2KMT2ANPSR1KDM4EMAPK1 | |
| SCHEMBL16756243 | 0.80 | ALPL (0.58) | SMN1; SMN2KMT2ANPSR1KDM4EMAPK1 | |
| SCHEMBL3397595 | 0.80 | ALPL (0.58) | SMN1; SMN2KMT2ANPSR1KDM4EMAPK1 | |
| SCHEMBL3156394 | 0.77 | KDM4E (0.71) | SMN1; SMN2MAPTKDM4EMAPK1CYP1A2 | |
| SCHEMBL2147079 | 0.73 | ALDH1A1 (0.66) | SMN1; SMN2KMT2ANPSR1KDM4EMAPK1 | |
| SCHEMBL14770674 | 0.72 | SMN1; SMN2 (0.56) | SMN1; SMN2KMT2AKDM4EMEN1MLKL | |
| SCHEMBL9453486 | 0.71 | RAB9A (0.63) | SMN1; SMN2KMT2AMAPTNPSR1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004063169-A1 | HYDROXAMID ACID DERIVATIVES AS HISTONE DEACETYLASE (HDAC) INHIBITORS | ASTELLAS PHARMA INC. (JP) | 2004-07-29 | — | — | WO | disclosed |