Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 1/20 | 0.36 |
| ▸ | BRD2 | P25440 | 1/20 | 0.36 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.36 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.35 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.35 |
| ▸ | FABP4 | P15090 | 6/20 | 0.33 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.33 |
| ▸ | DHFR | P00374 | 1/20 | 0.33 |
| ▸ | FABP5 | Q01469 | 4/20 | 0.32 |
| ▸ | MAOB | P27338 | 1/20 | 0.32 |
| ▸ | RXRA | P19793 | 1/20 | 0.32 |
| ▸ | RXRB | P28702 | 1/20 | 0.32 |
| ▸ | TDO2 | P48775 | 1/20 | 0.32 |
| ▸ | FABP3 | P05413 | 2/20 | 0.32 |
| ▸ | FABP1 | P07148 | 1/20 | 0.32 |
| ▸ | GCGR | P47871 | 1/20 | 0.32 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.31 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.31 |
| ▸ | AKR1C3 | P42330 | 2/20 | 0.31 |
| ▸ | AKR1C2 | P52895 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8647456 | 0.83 | FABP4 (0.35) | BRD4FABP4PTGS2AKR1C3AKR1C2 | |
| SCHEMBL8322952 | 0.82 | ENPP1 (0.35) | — | |
| SCHEMBL8322919 | 0.77 | ADORA2A (0.37) | ADORA2AADORA1MAOBRXRARXRB | |
| SCHEMBL244495 | 0.76 | KDM4E (0.40) | ADORA2AADORA1RXRARXRBAKR1C3 | |
| SCHEMBL8320388 | 0.71 | PTGS2 (0.39) | FABP4PTGS2RXRARXRBAKR1C3 | |
| SCHEMBL8318362 | 0.69 | PTPN1 (0.47) | FABP4PTGS2FABP5RXRARXRB | |
| SCHEMBL8322205 | 0.69 | ELANE (0.44) | PTGS2RXRARXRBAKR1C3AKR1C2 | |
| SCHEMBL10013789 | 0.69 | ACHE (0.52) | — | |
| SCHEMBL8648344 | 0.68 | PTGS2 (0.38) | PTGS2 | |
| SCHEMBL8383144 | 0.67 | TP53 (0.32) | BRD4BRD2CREBBP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5880169-A | HAVING HIGH RESOLUTION FOR FINE PATTERNING | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 1999-03-09 | — | — | US | disclosed |