Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOTUM | Q6P988 | 2/20 | 0.42 |
| ▸ | LCK | P06239 | 5/20 | 0.35 |
| ▸ | RET | P07949 | 5/20 | 0.35 |
| ▸ | KDR | P35968 | 5/20 | 0.35 |
| ▸ | LRRK2 | Q5S007 | 4/20 | 0.35 |
| ▸ | ALK | Q9UM73 | 4/20 | 0.35 |
| ▸ | PDGFRA | P16234 | 4/20 | 0.35 |
| ▸ | BAZ2B | Q9UIF8 | 6/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | GSK3A | P49840 | 5/20 | 0.35 |
| ▸ | GSK3B | P49841 | 5/20 | 0.35 |
| ▸ | PTAFR | P25105 | 1/20 | 0.33 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8325730 | 1.00 | NOTUM (0.42) | NOTUMLCKRETKDRLRRK2 | |
| SCHEMBL8329194 | 0.85 | ESR1 (0.44) | — | |
| SCHEMBL8329197 | 0.85 | ESR1 (0.44) | — | |
| SCHEMBL8328296 | 0.85 | NOTUM (0.46) | NOTUMLCKRETKDRLRRK2 | |
| SCHEMBL8325695 | 0.84 | MAOA (0.34) | LMNAMAPTGSK3B | |
| SCHEMBL8325697 | 0.84 | MAOA (0.34) | LMNAMAPTGSK3B | |
| SCHEMBL8328966 | 0.77 | ALDH1A1 (0.30) | — | |
| SCHEMBL8328965 | 0.77 | ALDH1A1 (0.30) | — | |
| SCHEMBL5095796 | 0.76 | BAZ2B (0.41) | LCKRETKDRLRRK2BAZ2B | |
| SCHEMBL8330143 | 0.76 | CD274 (0.37) | LMNAMAPTGSK3AGSK3B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0529636-B1 | Novel isatinoxime derivatives, their preparation and use | NEUROSEARCH AS (DK) | 1999-06-23 | — | — | EP | disclosed |
| US-5436250-A | Isatineoxime derivatives, their preparation and use | NEUROSEARCH A/S (DK) | 1995-07-25 | — | — | US | disclosed |
| US-5242918-A | Isatinoxime derivatives, their preparation and use | NEUROSEARCH A/S (DK) | 1993-09-07 | — | — | US | disclosed |
| EP-0529636-A1 | Novel isatinoxime derivatives, their preparation and use | NEUROSEARCH A/S (DK) | 1993-03-03 | — | — | EP | disclosed |