Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DHFR | P00374 | 1/20 | 0.41 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | GFER | P55789 | 1/20 | 0.35 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | KIF11 | P52732 | 1/20 | 0.31 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.31 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.31 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8321729 | 0.89 | DHFR (0.47) | DHFRHSD11B1NPC1RAB9AKDM4C | |
| SCHEMBL8322550 | 0.88 | GAA (0.37) | DHFRHSD11B1KDM4ESMN1; SMN2HSD17B10 | |
| SCHEMBL8322230 | 0.85 | DHFR (0.36) | DHFRHSD11B1ALDH1A1POLBKDM4C | |
| SCHEMBL8324624 | 0.85 | DHFR (0.43) | DHFRHSD11B1SMN1; SMN2ALDH1A1TP53 | |
| SCHEMBL8321358 | 0.82 | GAA (0.35) | DHFRHSD11B1KDM4ESMN1; SMN2HSD17B10 | |
| SCHEMBL6140343 | 0.81 | HSD11B1 (0.33) | DHFRHSD11B1KDM4ESMN1; SMN2HSD17B10 | |
| SCHEMBL8649667 | 0.80 | DHFR (0.35) | DHFRHSD11B1ALDH1A1POLBTSHR | |
| SCHEMBL8319157 | 0.79 | DHFR (0.39) | DHFRHSD11B1ALDH1A1NPC1RAB9A | |
| SCHEMBL8327555 | 0.79 | DDB1 (0.36) | DHFRHSD11B1SMN1; SMN2TP53NPC1 | |
| SCHEMBL6140379 | 0.78 | ALDH1A1 (0.33) | HSD11B1KDM4ESMN1; SMN2HSD17B10ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5880169-A | HAVING HIGH RESOLUTION FOR FINE PATTERNING | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 1999-03-09 | — | — | US | disclosed |