Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DHFR | P00374 | 1/20 | 0.43 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.37 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.33 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.33 |
| ▸ | HPGD | P15428 | 2/20 | 0.32 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.32 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.32 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 3/20 | 0.32 |
| ▸ | RAB9A | P51151 | 2/20 | 0.32 |
| ▸ | CTSD | P07339 | 1/20 | 0.31 |
| ▸ | BACE1 | P56817 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.30 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8321729 | 0.95 | DHFR (0.47) | DHFRHSD11B1KDM4CPDE4BSLC6A2 | |
| SCHEMBL8322550 | 0.87 | GAA (0.37) | DHFRHSD11B1HPGDTP53ALDH1A1 | |
| SCHEMBL8319788 | 0.86 | LMNA (0.36) | DHFRHSD11B1KDM4CPDE4BHPGD | |
| SCHEMBL8325993 | 0.85 | DHFR (0.41) | DHFRHSD11B1KDM4CPDE4BTP53 | |
| SCHEMBL8649231 | 0.84 | TP53 (0.41) | DHFRHSD11B1TP53RAB9ACTSD | |
| SCHEMBL8649686 | 0.83 | TSHR (0.38) | DHFRHSD11B1SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL8319157 | 0.83 | DHFR (0.39) | DHFRHSD11B1KDM4CSLC6A3RAB9A | |
| SCHEMBL3184997 | 0.82 | DHFR (0.53) | DHFRHSD11B1KDM4CPDE4BSLC6A2 | |
| SCHEMBL17120782 | 0.81 | DHFR (0.44) | DHFRHSD11B1KDM4CRAB9ANPC1 | |
| SCHEMBL8321358 | 0.81 | GAA (0.35) | DHFRHSD11B1HPGDTP53ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5880169-A | HAVING HIGH RESOLUTION FOR FINE PATTERNING | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 1999-03-09 | — | — | US | disclosed |