Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR3 | P51677 | 7/20 | 0.47 |
| ▸ | DRD4 | P21917 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 4/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | PDE2A | O00408 | 1/20 | 0.40 |
| ▸ | ROCK2 | O75116 | 2/20 | 0.40 |
| ▸ | CCR2 | P41597 | 1/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.40 |
| ▸ | MAOA | P21397 | 1/20 | 0.40 |
| ▸ | MAOB | P27338 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8326148 | 0.90 | LTA4H (0.45) | POLBMAOAMAOBKMT2AMEN1 | |
| SCHEMBL8326337 | 0.87 | POLB (0.49) | CCR3POLBMAOAMAOBKMT2A | |
| SCHEMBL8327678 | 0.85 | KMT2A (0.53) | POLBMAOAMAOBKMT2AMEN1 | |
| SCHEMBL8324361 | 0.85 | CYP1A2 (0.40) | POLBROCK2MAOAMAOBKMT2A | |
| SCHEMBL8329017 | 0.84 | ALDH1A1 (0.54) | POLBPDE2AMAOAMAOBKMT2A | |
| SCHEMBL8330452 | 0.84 | ALDH1A1 (0.43) | POLBPDE2AMAOAMAOBKMT2A | |
| SCHEMBL8330708 | 0.82 | KMT2A (0.52) | POLBKMT2AMEN1ALDH1A1 | |
| SCHEMBL7502764 | 0.82 | DRD4 (0.50) | CCR3DRD4 | |
| SCHEMBL8329545 | 0.77 | CCR3 (0.53) | CCR3DRD4POLBSMN1; SMN2CCR2 | |
| SCHEMBL8619286 | 0.77 | CCR3 (0.46) | CCR3DRD4POLBSMN1; SMN2PDE2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0760368-B1 | PYRIMIDINE DERIVATIVES | NISSHIN FLOUR MILLING CO (JP) | 1999-07-28 | — | — | EP | disclosed |
| EP-0760362-A1 | NOVEL DIAMINOMETHYLIDENE DERIVATIVE | NISSHIN FLOUR MILLING CO., LTD. (JP) | 1997-03-05 | — | — | EP | disclosed |
| EP-0760368-A1 | NOVEL PYRIMIDINE DERIVATIVE | NISSHIN FLOUR MILLING CO., LTD. (JP) | 1997-03-05 | — | — | EP | disclosed |