Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TBXAS1 | P24557 | 10/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.53 |
| ▸ | USP2 | O75604 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.53 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.53 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | CYP17A1 | P05093 | 3/20 | 0.40 |
| ▸ | CYP21A2 | P08686 | 3/20 | 0.40 |
| ▸ | CYP11B1 | P15538 | 3/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8319569 | 0.84 | TGFBR1 (0.44) | ALDH1A1 | |
| SCHEMBL22579296 | 0.81 | MAOB (0.43) | MEN1CYP3A4CYP2D6KMT2AALDH1A1 | |
| SCHEMBL15341322 | 0.81 | HDAC8 (0.43) | CYP1A2KMT2AALDH1A1 | |
| SCHEMBL15341321 | 0.80 | TRPV1 (0.46) | LMNAMEN1KMT2AALDH1A1 | |
| SCHEMBL38654486 | 0.80 | TRPM8 (0.41) | CYP1A2LMNAKMT2AALDH1A1 | |
| SCHEMBL4819507 | 0.80 | TRPM8 (0.41) | CYP1A2LMNAKMT2AALDH1A1 | |
| SCHEMBL8318572 | 0.79 | HDAC1 (0.50) | LMNACYP11B1 | |
| SCHEMBL26186289 | 0.78 | MGLL (0.41) | CYP1A2MEN1KMT2AALDH1A1 | |
| SCHEMBL1579761 | 0.78 | MGLL (0.43) | CYP1A2KMT2AALDH1A1 | |
| SCHEMBL1579763 | 0.78 | MGLL (0.43) | CYP1A2KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004063169-A1 | HYDROXAMID ACID DERIVATIVES AS HISTONE DEACETYLASE (HDAC) INHIBITORS | ASTELLAS PHARMA INC. (JP) | 2004-07-29 | — | — | WO | disclosed |