Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 3/20 | 0.43 |
| ▸ | MLLT1 | Q03111 | 1/20 | 0.41 |
| ▸ | ADH5 | P11766 | 1/20 | 0.40 |
| ▸ | PORCN | Q9H237 | 3/20 | 0.40 |
| ▸ | HTR2A | P28223 | 1/20 | 0.39 |
| ▸ | HTR2C | P28335 | 1/20 | 0.39 |
| ▸ | HTR2B | P41595 | 1/20 | 0.39 |
| ▸ | MGLL | Q99685 | 1/20 | 0.39 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | CYP17A1 | P05093 | 2/20 | 0.38 |
| ▸ | CYP21A2 | P08686 | 2/20 | 0.38 |
| ▸ | CYP11B1 | P15538 | 2/20 | 0.38 |
| ▸ | ESR1 | P03372 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | MITF | O75030 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22579300 | 0.89 | ADH5 (0.48) | MAOBMLLT1ADH5TGFBR1CYP17A1 | |
| SCHEMBL22641730 | 0.82 | MAPT (0.48) | MAOBMGLLTGFBR1HTTKDM4E | |
| SCHEMBL22641675 | 0.82 | MAPT (0.47) | MGLLTGFBR1KDM4EMEN1MAPT | |
| SCHEMBL8326205 | 0.81 | TBXAS1 (0.53) | CYP3A4CYP2D6CYP17A1CYP21A2CYP11B1 | |
| SCHEMBL38654486 | 0.80 | TRPM8 (0.41) | MAOBMGLLTGFBR1KDM4EALDH1A1 | |
| SCHEMBL4819507 | 0.80 | TRPM8 (0.41) | MAOBMGLLTGFBR1KDM4EALDH1A1 | |
| SCHEMBL22641744 | 0.80 | TGFBR1 (0.36) | MGLLTGFBR1 | |
| SCHEMBL22641632 | 0.79 | HDAC3 (0.50) | MGLLESR1KDM4EMAPT | |
| SCHEMBL1579761 | 0.78 | MGLL (0.43) | MAOBMGLLTGFBR1ESR1KDM4E | |
| SCHEMBL1579763 | 0.78 | MGLL (0.43) | MAOBMGLLTGFBR1ESR1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200331882-A1 | COMPOUND FOR SIMULTANEOUSLY INHIBITING LSD1 AND HDAC TARGETS AND APPLICATION THEREOF | PEKING UNIVERSITY SHENZHEN GRADUATE SCHOOL (CN) | 2020-10-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200331882-A1 | COMPOUND FOR SIMULTANEOUSLY INHIBITING LSD1 AND HDAC TARGETS AND APPLICATION THEREOF | HDAC1, HDAC3, HDAC11 | MAOB 295/4885MLLT1 203/4885ADH5 2317/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.