Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 3/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | CNR2 | P34972 | 4/20 | 0.40 |
| ▸ | CNR1 | P21554 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | ABCC1 | P33527 | 1/20 | 0.40 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.40 |
| ▸ | PDE5A | O76074 | 1/20 | 0.39 |
| ▸ | BRD4 | O60885 | 1/20 | 0.39 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.39 |
| ▸ | OGG1 | O15527 | 1/20 | 0.38 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8331488 | 0.84 | L3MBTL1 (0.51) | KDM4ELMNAMAPK1NPC1RAB9A | |
| SCHEMBL8330157 | 0.79 | PRNP (0.45) | KDM4ELMNAMAPK1RAB9ACNR2 | |
| SCHEMBL8328519 | 0.77 | PTGS2 (0.47) | KDM4ELMNAMAPK1NPC1RAB9A | |
| SCHEMBL8327817 | 0.77 | CD274 (0.55) | KDM4ELMNAMAPK1NPC1RAB9A | |
| SCHEMBL8330931 | 0.73 | CD274 (0.41) | KDM4ELMNAMAPK1NPC1RAB9A | |
| SCHEMBL4094953 | 0.71 | RPS6KB1 (0.50) | CNR2ABCC1ABCG2 | |
| SCHEMBL7217363 | 0.71 | TSHR (0.41) | KDM4EMAPK1NPC1GAACYP1A2 | |
| SCHEMBL8331863 | 0.70 | ALOX5 (0.41) | KDM4ELMNAMAPK1NPC1RAB9A | |
| SCHEMBL8332494 | 0.70 | KDM4E (0.42) | KDM4ENPC1RAB9ASMN1; SMN2GAA | |
| SCHEMBL8332147 | 0.70 | KDM4E (0.44) | KDM4ENPC1RAB9AGAAHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5994270-A | CONTROLLING GAEUMANNOMYCES | MONSANTO COMPANY (US) | 1999-11-30 | — | — | US | disclosed |
| EP-0619297-B1 | Fungicides for the control of take-all desease of plants | MONSANTO CO (US) | 1997-06-18 | — | — | EP | disclosed |
| EP-0619297-A1 | Fungicides for the control of take-all desease of plants | MONSANTO COMPANY (US) | 1994-10-12 | — | — | EP | disclosed |