Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 2/20 | 0.47 |
| ▸ | NPC1 | O15118 | 5/20 | 0.46 |
| ▸ | HPGD | P15428 | 4/20 | 0.46 |
| ▸ | MAPT | P10636 | 5/20 | 0.45 |
| ▸ | RAB9A | P51151 | 5/20 | 0.45 |
| ▸ | LMNA | P02545 | 3/20 | 0.45 |
| ▸ | GAA | P10253 | 3/20 | 0.45 |
| ▸ | OGG1 | O15527 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.42 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.42 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | PPARG | P37231 | 1/20 | 0.42 |
| ▸ | NR2E3 | Q9Y5X4 | 1/20 | 0.42 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9024182 | 0.77 | SENP5 (0.58) | PTGS2HPGDMAPTLMNAGAA | |
| SCHEMBL8326221 | 0.77 | KDM4E (0.46) | PTGS2NPC1HPGDMAPTRAB9A | |
| SCHEMBL7217566 | 0.71 | HPGD (0.41) | NPC1HPGDMAPTRAB9ALMNA | |
| SCHEMBL8326252 | 0.70 | NPC1 (0.48) | NPC1RAB9ALMNAGAAALDH1A1 | |
| SCHEMBL26575957 | 0.70 | CYP1A2 (0.56) | NPC1HPGDMAPTRAB9ALMNA | |
| SCHEMBL6360786 | 0.70 | PTGS2 (0.51) | PTGS2NPC1HPGDMAPTRAB9A | |
| SCHEMBL24898755 | 0.69 | MAPT (0.60) | MAPTLMNASMN1; SMN2TP53 | |
| SCHEMBL8331357 | 0.67 | NPC1 (0.47) | NPC1HPGDMAPTRAB9ALMNA | |
| SCHEMBL8329059 | 0.67 | CYP1A2 (0.72) | NPC1HPGDMAPTRAB9ALMNA | |
| SCHEMBL490124 | 0.67 | ALDH1A1 (0.44) | NPC1HPGDMAPTRAB9ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5994270-A | CONTROLLING GAEUMANNOMYCES | MONSANTO COMPANY (US) | 1999-11-30 | — | — | US | disclosed |
| EP-0619297-B1 | Fungicides for the control of take-all desease of plants | MONSANTO CO (US) | 1997-06-18 | — | — | EP | disclosed |
| EP-0619297-A1 | Fungicides for the control of take-all desease of plants | MONSANTO COMPANY (US) | 1994-10-12 | — | — | EP | disclosed |