Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 1/20 | 0.41 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.41 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.41 |
| ▸ | HPGDS | O60760 | 1/20 | 0.41 |
| ▸ | ESR1 | P03372 | 1/20 | 0.41 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 4/20 | 0.40 |
| ▸ | HDAC3 | O15379 | 3/20 | 0.40 |
| ▸ | HDAC8 | Q9BY41 | 3/20 | 0.40 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.40 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.39 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.39 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.38 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.38 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.38 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.38 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8324383 | 0.89 | ESR1 (0.51) | HPGDSESR1NPY5RHDAC1HDAC3 | |
| SCHEMBL8319501 | 0.76 | THRB (0.54) | ESR1HDAC1HDAC3HDAC8HDAC2 | |
| SCHEMBL8319321 | 0.69 | HDAC3 (0.42) | ALOX5PTGS1PTGS2HDAC1HDAC3 | |
| SCHEMBL8324034 | 0.69 | RECQL (0.45) | ESR1HDAC1HDAC3HDAC8HDAC2 | |
| SCHEMBL8325145 | 0.68 | GRIN1 (0.52) | ALOX5PTGS1PTGS2HDAC1HDAC3 | |
| SCHEMBL8323117 | 0.67 | HDAC1 (0.52) | HDAC1HDAC3HDAC8HDAC2HDAC6 | |
| SCHEMBL28265975 | 0.66 | NPY5R (0.62) | NPY5R | |
| SCHEMBL8327745 | 0.66 | HDAC2 (0.56) | HDAC1HDAC3HDAC8HDAC2HDAC6 | |
| SCHEMBL8320427 | 0.65 | HDAC2 (0.56) | HDAC1HDAC3HDAC8HDAC2HDAC6 | |
| SCHEMBL8325738 | 0.65 | HPGDS (0.43) | HPGDSHDAC1HDAC3HDAC8HDAC2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004063169-A1 | HYDROXAMID ACID DERIVATIVES AS HISTONE DEACETYLASE (HDAC) INHIBITORS | ASTELLAS PHARMA INC. (JP) | 2004-07-29 | — | — | WO | disclosed |