Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 13/20 | 0.50 |
| ▸ | MAOB | P27338 | 4/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
| ▸ | BCHE | P06276 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8326721 | 0.99 | MAOB (0.49) | ACHEMAOBALDH1A1KMT2AHSD17B10 | |
| SCHEMBL8329022 | 0.96 | ALDH1A1 (0.50) | ACHEMAOBALDH1A1KMT2AHSD17B10 | |
| SCHEMBL8325503 | 0.90 | SMN1; SMN2 (0.46) | ACHEMAOBALDH1A1KMT2AHSD17B10 | |
| SCHEMBL8330108 | 0.87 | NPC1 (0.45) | ACHEMAOBALDH1A1KMT2AHSD17B10 | |
| SCHEMBL25047644 | 0.87 | ALDH1A1 (0.49) | ACHEMAOBALDH1A1KMT2AHSD17B10 | |
| SCHEMBL31618003 | 0.87 | ALDH1A1 (0.49) | ACHEMAOBALDH1A1KMT2AHSD17B10 | |
| SCHEMBL7950278 | 0.86 | ACHE (0.50) | ACHEMAOBBCHE | |
| SCHEMBL25797675 | 0.85 | MAOB (0.49) | ACHEMAOBBCHE | |
| SCHEMBL2083798 | 0.83 | ACHE (0.46) | ACHEMAOBBCHE | |
| SCHEMBL13784833 | 0.82 | MAOB (0.51) | ACHEMAOBALDH1A1KMT2ABCHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0760368-B1 | PYRIMIDINE DERIVATIVES | NISSHIN FLOUR MILLING CO (JP) | 1999-07-28 | — | — | EP | disclosed |
| US-5736550-A | TREATMENT OF GASTROINTESTINAL TRACT DISORDERS | NISSHIN FLOUR MILLING CO., LTD. (JP) | 1998-04-07 | — | — | US | disclosed |
| EP-0760368-A1 | NOVEL PYRIMIDINE DERIVATIVE | NISSHIN FLOUR MILLING CO., LTD. (JP) | 1997-03-05 | — | — | EP | disclosed |