Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | MAOB | P27338 | 6/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | ACHE | P22303 | 3/20 | 0.40 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.40 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.40 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.40 |
| ▸ | CASP3 | P42574 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8329022 | 0.92 | ALDH1A1 (0.50) | SMN1; SMN2ALDH1A1KMT2AHSD17B10MAOB | |
| SCHEMBL8326721 | 0.91 | MAOB (0.49) | ALDH1A1KMT2AHSD17B10MAOBPOLB | |
| SCHEMBL8326801 | 0.90 | ACHE (0.50) | ALDH1A1KMT2AHSD17B10MAOBACHE | |
| SCHEMBL8330108 | 0.89 | NPC1 (0.45) | SMN1; SMN2ALDH1A1KMT2AHSD17B10MAOB | |
| SCHEMBL25047644 | 0.84 | ALDH1A1 (0.49) | SMN1; SMN2ALDH1A1KMT2AHSD17B10MAOB | |
| SCHEMBL31618003 | 0.84 | ALDH1A1 (0.49) | SMN1; SMN2ALDH1A1KMT2AHSD17B10MAOB | |
| SCHEMBL19545291 | 0.81 | MAPK1 (0.43) | SMN1; SMN2ALDH1A1KMT2AHSD17B10POLB | |
| SCHEMBL31439885 | 0.81 | MAOB (0.43) | SMN1; SMN2ALDH1A1KMT2AHSD17B10MAOB | |
| SCHEMBL13314039 | 0.81 | MAOB (0.48) | ALDH1A1KMT2AHSD17B10MAOBMEN1 | |
| SCHEMBL8328376 | 0.80 | CASP3 (0.40) | SMN1; SMN2ALDH1A1KMT2AHSD17B10POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0760368-B1 | PYRIMIDINE DERIVATIVES | NISSHIN FLOUR MILLING CO (JP) | 1999-07-28 | — | — | EP | disclosed |
| EP-0559774-B1 | INDIVIDUAL STEREOISOMERS OF 7- 3-(1-AMINOALKYL)-1-PYRROLIDINYL]-QUINOLONES AND NAPHTHYRIDONES AS ANTIBACTERIAL AGENTS | WARNER LAMBERT CO (US) | 1999-07-07 | — | — | EP | disclosed |
| EP-0909759-A2 | Individual stereoisomers of 7-(3-aminoalkyl)-1-pyrrolidinyl)-quinolones as antibacterial agents | WARNER-LAMBERT COMPANY (US) | 1999-04-21 | — | — | EP | disclosed |
| US-5736550-A | TREATMENT OF GASTROINTESTINAL TRACT DISORDERS | NISSHIN FLOUR MILLING CO., LTD. (JP) | 1998-04-07 | — | — | US | disclosed |
| EP-0760368-A1 | NOVEL PYRIMIDINE DERIVATIVE | NISSHIN FLOUR MILLING CO., LTD. (JP) | 1997-03-05 | — | — | EP | disclosed |
| US-5258528-A | Bactericides | WARNER-LAMBERT COMPANY (US) | 1993-11-02 | — | — | US | disclosed |