Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | MAOB | P27338 | 6/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | ACHE | P22303 | 6/20 | 0.45 |
| ▸ | BCHE | P06276 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8326721 | 0.97 | MAOB (0.49) | ALDH1A1KMT2AHSD17B10POLBMAOB | |
| SCHEMBL8326801 | 0.96 | ACHE (0.50) | ALDH1A1KMT2AHSD17B10MAOBACHE | |
| SCHEMBL8325503 | 0.92 | SMN1; SMN2 (0.46) | ALDH1A1KMT2AHSD17B10POLBMAOB | |
| SCHEMBL25047644 | 0.91 | ALDH1A1 (0.49) | ALDH1A1KMT2AHSD17B10POLBMAOB | |
| SCHEMBL31618003 | 0.91 | ALDH1A1 (0.49) | ALDH1A1KMT2AHSD17B10POLBMAOB | |
| SCHEMBL8330108 | 0.89 | NPC1 (0.45) | ALDH1A1KMT2AHSD17B10POLBMAOB | |
| SCHEMBL19925980 | 0.86 | MAOB (0.49) | ALDH1A1KMT2AHSD17B10MAOBACHE | |
| SCHEMBL25797675 | 0.84 | MAOB (0.49) | MAOBACHEBCHE | |
| SCHEMBL30941004 | 0.81 | TDP1 (0.53) | MAOBACHEBCHE | |
| SCHEMBL19545291 | 0.81 | MAPK1 (0.43) | ALDH1A1KMT2AHSD17B10POLBSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0760368-B1 | PYRIMIDINE DERIVATIVES | NISSHIN FLOUR MILLING CO (JP) | 1999-07-28 | — | — | EP | disclosed |
| US-5736550-A | TREATMENT OF GASTROINTESTINAL TRACT DISORDERS | NISSHIN FLOUR MILLING CO., LTD. (JP) | 1998-04-07 | — | — | US | disclosed |
| EP-0760368-A1 | NOVEL PYRIMIDINE DERIVATIVE | NISSHIN FLOUR MILLING CO., LTD. (JP) | 1997-03-05 | — | — | EP | disclosed |