Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | GLA | P06280 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | TNF | P01375 | 1/20 | 0.34 |
| ▸ | BRD4 | O60885 | 1/20 | 0.34 |
| ▸ | BRD2 | P25440 | 1/20 | 0.34 |
| ▸ | BRD3 | Q15059 | 1/20 | 0.34 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.34 |
| ▸ | LPO | P22079 | 3/20 | 0.34 |
| ▸ | LMNA | P02545 | 3/20 | 0.34 |
| ▸ | HPGD | P15428 | 2/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9837290 | 0.76 | HDAC6 (0.34) | KMT2ACYP2C9LMNAKEAP1NFE2L2 | |
| SCHEMBL12684180 | 0.69 | LPO (0.38) | KMT2ARAB9ASMN1; SMN2CYP1A2ALDH1A1 | |
| SCHEMBL29722269 | 0.69 | LPO (0.35) | KMT2ARAB9ASMN1; SMN2CYP1A2ALDH1A1 | |
| SCHEMBL23147508 | 0.69 | LPO (0.35) | KMT2ARAB9ASMN1; SMN2CYP1A2ALDH1A1 | |
| SCHEMBL3977245 | 0.69 | ALDH1A1 (0.53) | KMT2ANPC1RAB9ASMN1; SMN2ALDH1A1 | |
| SCHEMBL12009953 | 0.69 | PARP1 (0.40) | KMT2ARAB9ASMN1; SMN2CYP1A2LPO | |
| SCHEMBL4827306 | 0.69 | RAB9A (0.40) | KMT2ARAB9ASMN1; SMN2CYP1A2ALDH1A1 | |
| SCHEMBL8091107 | 0.68 | NPC1 (0.48) | KMT2ANPC1RAB9ASMN1; SMN2ALDH1A1 | |
| SCHEMBL9536041 | 0.68 | NPC1 (0.46) | KMT2ANPC1ALDH1A1KDM4ECYP2C19 | |
| SCHEMBL19986908 | 0.68 | ALDH1A1 (0.49) | KMT2ANPC1SMN1; SMN2ALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0930297-A1 | A process for preparing naphthyridones and intermediates | Pfizer Products Inc. (US) | 1999-07-21 | — | — | EP | disclosed |