Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 10/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 9/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 9/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 4/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.36 |
| ▸ | HTR2C | P28335 | 2/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 8/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.34 |
| ▸ | RBP4 | P02753 | 4/20 | 0.34 |
| ▸ | TSHR | P16473 | 3/20 | 0.33 |
| ▸ | USP2 | O75604 | 2/20 | 0.33 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.33 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | ACP3 | P15309 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8441351 | 0.77 | CYP3A4 (0.37) | CYP3A4CYP2D6CYP2C19ALOX15HSD17B10 | |
| SCHEMBL8828275 | 0.75 | CYP3A4 (0.39) | CYP3A4CYP2D6CYP2C19ALOX15HSD17B10 | |
| SCHEMBL30903830 | 0.73 | ACP3 (0.50) | ALDH1A1TDP1ACP3LMNAIDO1 | |
| SCHEMBL9776265 | 0.73 | ACP3 (0.50) | ALDH1A1TDP1ACP3LMNAIDO1 | |
| SCHEMBL8745914 | 0.73 | ACP3 (0.43) | CYP3A4CYP2D6CYP2C19ALOX15HSD17B10 | |
| SCHEMBL8329113 | 0.72 | RBP4 (0.44) | CYP3A4CYP2D6CYP2C19ALOX15HSD17B10 | |
| SCHEMBL8578908 | 0.71 | CYP1A2 (0.34) | CYP3A4CYP2D6CYP2C19ALOX15ALDH1A1 | |
| SCHEMBL8546018 | 0.69 | TNF (0.38) | HSD17B10ALDH1A1RBP4ACP3KDM4E | |
| SCHEMBL8745920 | 0.67 | PIEZO1 (0.38) | CYP3A4MEN1KMT2AACP3 | |
| Benzyl Alcohol SCHEMBL27535788 | 0.67 | CYP3A4 (0.38) | CYP3A4CYP2D6CYP2C19ALOX15HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1230943-A | Process for the preparation of aryl-beta-diketones, aryl-pyrimidinones and crop protection intermediates | ZENECA LTD (GB) | 1999-10-06 | — | — | CN | disclosed |
| EP-0929510-A2 | PROCESSES FOR THE PREPARATION OF ARYL-$g(b)-DIKETONES, ARYL-PYRIMIDINE KETONES AND CROP PROTECTION INTERMEDIATES | ZENECA LIMITED (GB) | 1999-07-21 | — | — | EP | disclosed |
| US-5925795-A | Processes for the preparation of aryl-β-diketones, arylpyrimidine ketones and crop protection intermediates | ZENECA LIMITED (GB) | 1999-07-20 | — | — | US | disclosed |
| EP-0927169-A1 | 4-CYCLOALKYL-5-SUBSTITUTED PYRIMIDINE COMPOUNDS USEFUL AS CROP PROTECTION AGENTS | ZENECA LIMITED (GB) | 1999-07-07 | — | — | EP | disclosed |
| WO-1998011046-A2 | PROCESSES FOR THE PREPARATION OF ARYL-β-DIKETONES, ARYL-PYRIMIDINE KETONES AND CROP PROTECTION INTERMEDIATES | ZENECA LIMITED (GB) | 1998-03-19 | — | — | WO | disclosed |
| WO-1998011074-A1 | 4-CYCLOALKYL-5-SUBSTITUTED PYRIMIDINE COMPOUNDS USEFUL AS CROP PROTECTION AGENTS | ZENECA LIMITED (GB) | 1998-03-19 | — | — | WO | disclosed |
| US-5707930-A | HERBICIDES, AGRICULTURE | ZENECA LIMITED (GB) | 1998-01-13 | — | — | US | disclosed |