Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCL2 | P10415 | 1/20 | 0.36 |
| ▸ | BAD | Q92934 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.34 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.34 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.34 |
| ▸ | CCNE2 | O96020 | 2/20 | 0.32 |
| ▸ | CCNE1 | P24864 | 2/20 | 0.32 |
| ▸ | CDK2 | P24941 | 2/20 | 0.32 |
| ▸ | CDK4 | P11802 | 1/20 | 0.31 |
| ▸ | CCND1 | P24385 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8329192 | 1.00 | BCL2 (0.36) | BCL2BADMEN1HPGDKMT2A | |
| SCHEMBL8328971 | 0.91 | GABRP (0.38) | — | |
| SCHEMBL8327852 | 0.89 | MEN1 (0.36) | BCL2BADMEN1HPGDKMT2A | |
| SCHEMBL8350166 | 0.86 | CDK4 (0.36) | BCL2BADMEN1HPGDKMT2A | |
| SCHEMBL8347791 | 0.86 | CDK4 (0.36) | BCL2BADMEN1HPGDKMT2A | |
| SCHEMBL8330780 | 0.83 | CCNE2 (0.38) | BCL2BADMEN1HPGDKMT2A | |
| SCHEMBL7608894 | 0.82 | BCL2 (0.36) | BCL2BADOPRM1OPRD1OPRK1 | |
| SCHEMBL8326640 | 0.80 | GABRB3 (0.38) | — | |
| SCHEMBL8351551 | 0.77 | GABRP (0.43) | — | |
| SCHEMBL8784237 | 0.75 | MEN1 (0.36) | BCL2BADMEN1HPGDKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5968944-A | TREATING STRESS AND ANXIETY RELATED DISORDERS | PFIZER INC. (US) | 1999-10-19 | — | — | US | disclosed |