Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCHE | P06276 | 1/20 | 0.36 |
| ▸ | TYR | P14679 | 1/20 | 0.36 |
| ▸ | ACHE | P22303 | 1/20 | 0.36 |
| ▸ | ACP3 | P15309 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 3/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.34 |
| ▸ | MTNR1A | P48039 | 3/20 | 0.34 |
| ▸ | MTNR1B | P49286 | 3/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.33 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.32 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8329837 | 0.91 | MEN1 (0.37) | BCHETYRACHEACP3MEN1 | |
| SCHEMBL8334159 | 0.74 | ALDH1A1 (0.53) | MEN1KMT2ALMNAL3MBTL1GAA | |
| SCHEMBL6550407 | 0.70 | MEN1 (0.48) | BCHETYRACHEMEN1KMT2A | |
| SCHEMBL3823999 | 0.70 | TYR (0.52) | BCHETYRACHEACP3LMNA | |
| SCHEMBL11857411 | 0.70 | ACP3 (0.42) | BCHETYRACHEACP3MEN1 | |
| SCHEMBL18818974 | 0.69 | NOS2 (0.46) | BCHETYRACHEACP3MEN1 | |
| SCHEMBL5779727 | 0.69 | EPHX2 (0.45) | ACP3MEN1KMT2AMTNR1AMTNR1B | |
| SCHEMBL8806213 | 0.68 | ADRA2A (0.57) | MEN1KMT2ALMNACYP2D6 | |
| SCHEMBL29048103 | 0.68 | BCHE (0.46) | BCHETYRACHEACP3MEN1 | |
| SCHEMBL30943709 | 0.68 | ADRA2A (0.57) | MEN1KMT2ALMNACYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1998038182-A9 | HYPOLIPIDEMIC BICYCLIC DERIVATIVES | GLAXO GROUP LTD (GB) | 1999-04-15 | — | — | WO | disclosed |
| WO-1998038182-A1 | HYPOLIPIDEMIC BICYCLIC DERIVATIVES | GLAXO GROUP LIMITED (GB) | 1998-09-03 | — | — | WO | disclosed |