Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIN1 | Q13526 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.35 |
| ▸ | RECQL | P46063 | 1/20 | 0.35 |
| ▸ | MMP8 | P22894 | 1/20 | 0.35 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.35 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.35 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.35 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.35 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | BRD4 | O60885 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8327633 | 0.92 | TSHR (0.39) | PIN1TSHRNPC1LMNAGAA | |
| SCHEMBL8332116 | 0.86 | PIN1 (0.36) | PIN1TSHRALDH1A1RECQLMMP8 | |
| SCHEMBL8329338 | 0.82 | PIN1 (0.42) | PIN1TSHRLMNAGAAALDH1A1 | |
| SCHEMBL8329336 | 0.77 | LMNA (0.44) | PIN1TSHRNPC1LMNAGAA | |
| SCHEMBL8332643 | 0.77 | PIN1 (0.39) | PIN1TSHRALDH1A1RECQLMMP8 | |
| SCHEMBL8330071 | 0.76 | SMN1; SMN2 (0.44) | PIN1TSHRLMNAALDH1A1SMN1; SMN2 | |
| SCHEMBL3739399 | 0.75 | TSHR (0.48) | PIN1TSHRNPC1LMNAGAA | |
| SCHEMBL8327638 | 0.75 | PIN1 (0.41) | PIN1TSHRNPC1LMNAGAA | |
| SCHEMBL17007916 | 0.72 | SMN1; SMN2 (0.40) | PIN1TSHRNPC1LMNAGAA | |
| SCHEMBL8332642 | 0.71 | CASP1 (0.40) | PIN1TSHRGAAALDH1A1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5908863-A | ANTIGROWTH AGENT FOR BONES | DOMPE' S.P.A. (IT) | 1999-06-01 | — | — | US | disclosed |
| EP-0792878-A2 | Geminal carboxylic acids and esters thereof, pharmaceutical formulations containing them useful in the treatment of bone dysmetabolism | Dompé S.P.A. (IT) | 1997-09-03 | — | — | EP | disclosed |