Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIN1 | Q13526 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 4/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | MMP8 | P22894 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.39 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.39 |
| ▸ | HTR2A | P28223 | 1/20 | 0.39 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.39 |
| ▸ | PPARA | Q07869 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | BRD4 | O60885 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | HPGD | P15428 | 3/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8332118 | 0.84 | TP53 (0.39) | PIN1TSHRTP53MMP8CYP1A2 | |
| SCHEMBL17007916 | 0.82 | SMN1; SMN2 (0.40) | PIN1TSHRNPC1LMNATP53 | |
| SCHEMBL3739399 | 0.81 | TSHR (0.48) | PIN1TSHRNPC1LMNACYP1A2 | |
| SCHEMBL8329339 | 0.80 | LMNA (0.47) | PIN1TSHRNPC1LMNATP53 | |
| SCHEMBL8327633 | 0.79 | TSHR (0.39) | PIN1TSHRNPC1LMNATP53 | |
| SCHEMBL27682770 | 0.77 | CHRM2 (0.56) | PIN1LMNAMMP8GAAMEN1 | |
| SCHEMBL25230166 | 0.76 | ABCB11 (0.42) | PIN1TSHRNPC1LMNACYP1A2 | |
| SCHEMBL30486599 | 0.76 | ABCB11 (0.42) | PIN1TSHRNPC1LMNACYP1A2 | |
| SCHEMBL30711682 | 0.75 | CYP4F2 (0.41) | PIN1TSHRNPC1LMNATP53 | |
| SCHEMBL8327636 | 0.75 | PIN1 (0.40) | PIN1TSHRNPC1LMNAMMP8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5908863-A | ANTIGROWTH AGENT FOR BONES | DOMPE' S.P.A. (IT) | 1999-06-01 | — | — | US | disclosed |
| EP-0792878-A2 | Geminal carboxylic acids and esters thereof, pharmaceutical formulations containing them useful in the treatment of bone dysmetabolism | Dompé S.P.A. (IT) | 1997-09-03 | — | — | EP | disclosed |