Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR3 | P51677 | 8/20 | 0.43 |
| ▸ | DRD4 | P21917 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 3/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | LTA4H | P09960 | 1/20 | 0.37 |
| ▸ | PDE2A | O00408 | 1/20 | 0.37 |
| ▸ | ROCK2 | O75116 | 2/20 | 0.36 |
| ▸ | CCR2 | P41597 | 1/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.36 |
| ▸ | MAOA | P21397 | 1/20 | 0.36 |
| ▸ | MAOB | P27338 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8321744 | 0.91 | LTA4H (0.44) | DRD4POLBLTA4HMAOAMAOB | |
| SCHEMBL8328418 | 0.88 | POLB (0.44) | CCR3POLBLTA4HMAOAMAOB | |
| SCHEMBL8328227 | 0.87 | KMT2A (0.48) | POLBLTA4HMAOAMAOBKMT2A | |
| SCHEMBL8330578 | 0.86 | CYP1A2 (0.36) | POLBLTA4HROCK2MAOAMAOB | |
| SCHEMBL8329441 | 0.86 | ALDH1A1 (0.49) | POLBPDE2AMAOAMAOBKMT2A | |
| SCHEMBL8328811 | 0.86 | ALDH1A1 (0.39) | POLBLTA4HPDE2AMAOAMAOB | |
| SCHEMBL8321787 | 0.84 | KMT2A (0.46) | POLBLTA4HMAOBKMT2AMEN1 | |
| SCHEMBL8327166 | 0.84 | DRD4 (0.47) | CCR3DRD4 | |
| SCHEMBL8327681 | 0.81 | DRD4 (0.41) | DRD4POLBSMN1; SMN2PDE2AROCK2 | |
| SCHEMBL8328374 | 0.78 | ACHE (0.42) | KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5981130-A | Positively-chargeable charge control agent and toner for developing electrostatic images | ORIENT CHEMICAL INDUSTRIES, LTD. (JP) | 1999-11-09 | — | — | US | disclosed |
| EP-0760368-B1 | PYRIMIDINE DERIVATIVES | NISSHIN FLOUR MILLING CO (JP) | 1999-07-28 | — | — | EP | disclosed |
| EP-0881545-A1 | Positively-chargeable charge control agent and toner for developing electrostatic images | ORIENT CHEMICAL INDUSTRIES, LTD. (JP) | 1998-12-02 | — | — | EP | disclosed |
| US-5736550-A | TREATMENT OF GASTROINTESTINAL TRACT DISORDERS | NISSHIN FLOUR MILLING CO., LTD. (JP) | 1998-04-07 | — | — | US | disclosed |
| EP-0760368-A1 | NOVEL PYRIMIDINE DERIVATIVE | NISSHIN FLOUR MILLING CO., LTD. (JP) | 1997-03-05 | — | — | EP | disclosed |