Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8328418 | 0.90 | POLB (0.44) | MEN1KMT2A | |
| SCHEMBL8327173 | 0.87 | PRKAA2 (0.42) | ACHE | |
| SCHEMBL8324755 | 0.85 | SIGMAR1 (0.37) | ACHE | |
| SCHEMBL8326767 | 0.83 | DRD4 (0.47) | MEN1KMT2A | |
| SCHEMBL8326581 | 0.82 | SPHK2 (0.34) | — | |
| SCHEMBL8327922 | 0.82 | BCHE (0.35) | ACHEMEN1KMT2A | |
| SCHEMBL8321744 | 0.81 | LTA4H (0.44) | MEN1KMT2A | |
| SCHEMBL8328811 | 0.80 | ALDH1A1 (0.39) | ACHEMEN1KMT2A | |
| SCHEMBL8328227 | 0.79 | KMT2A (0.48) | ACHEMEN1KMT2A | |
| SCHEMBL8328991 | 0.79 | ALDH1A1 (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0760368-B1 | PYRIMIDINE DERIVATIVES | NISSHIN FLOUR MILLING CO (JP) | 1999-07-28 | — | — | EP | disclosed |
| US-5736550-A | TREATMENT OF GASTROINTESTINAL TRACT DISORDERS | NISSHIN FLOUR MILLING CO., LTD. (JP) | 1998-04-07 | — | — | US | disclosed |
| EP-0760368-A1 | NOVEL PYRIMIDINE DERIVATIVE | NISSHIN FLOUR MILLING CO., LTD. (JP) | 1997-03-05 | — | — | EP | disclosed |