SCHEMBL832785

SCHEMBL832785

CC(O)C(CC(=O)O)C(C)O

nearest known ligand 0.60

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
SLC22A6 Q4U2R8 1/20 0.50
SMN1; SMN2 Q16637 1/20 0.46
MAPT P10636 1/20 0.42
GABRR1 P24046 2/20 0.42
LMNA P02545 1/20 0.42
TDP1 Q9NUW8 1/20 0.41
TP53 P04637 1/20 0.40
CACNA2D1 P54289 2/20 0.39
CACNB3 P54284 1/20 0.39
CACNA1C Q13936 1/20 0.39
PGR P06401 1/20 0.39
ADRA1A P35348 1/20 0.39
HTR2B P41595 1/20 0.39
CACNA2D2 Q9NY47 1/20 0.39
GPR84 Q9NQS5 4/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28533319 0.79 GPR84 (0.42) SLC22A6SMN1; SMN2MAPTGABRR1TDP1
SCHEMBL17956711 0.79 GABRP (0.45) SLC22A6SMN1; SMN2GPR84
SCHEMBL765893 0.79 SLC22A6 (0.45) SLC22A6SMN1; SMN2MAPTGABRR1LMNA
3-Hydroxybutyric Acid, (+/-)- SCHEMBL16098949 0.79
(R)-3-Hydroxybutanoate SCHEMBL19459353 0.79
SCHEMBL3575582 0.77
SCHEMBL4854472 0.77
SCHEMBL2685811 0.77
3-Hydroxybutyric Acid, (+/-)- SCHEMBL21225058 0.77 SLC22A6 (0.50) SLC22A6SMN1; SMN2MAPTGABRR1LMNA
SCHEMBL1079959 0.77

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 45 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2016109193-A1 COATED PROPPANTS CONTAINING HYPERBRANCHED POLYURETHANE COATINGS AND METHODS FOR USING SAME GEORGIA-PACIFIC CHEMICALS LLC (US) 2016-07-07 WO claimed
US-20160186049-A1 COATED PROPPANTS CONTAINING HYPERBRANCHED POLYURETHANE COATINGS AND METHODS FOR USING SAME GEORGIA-PACIFIC CHEMICALS LLC (US) 2016-06-30 US claimed
US-20110045741-A1 Auto-Stopping Abrasive Composition for Polishing High Step Height Oxide Layer TECHNO SEMICHEM CO., LTD. (KR) 2011-02-24 US claimed
US-20090149596-A1 WATER DISPERSIBLE, HYDROXYL-TERMINATED, FLUORINATED POLYURETHANES AND METHOD OF PREPARING THE SAME PRC-DESOTO INTERNATIONAL, INC. 2009-06-11 US claimed
WO-2006115393-A1 AUTO-STOPPING ABRASIVE COMPOSITION FOR POLISHING HIGH STEP HEIGHT OXIDE LAYER TECHNO SEMICHEM CO., LTD. (KR) 2006-11-02 WO claimed
US-6174956-B1 POLYURETHANES IN DISPERSANTS AND CHAIN EXTENSION NATIONAL STARCH AND CHEMICAL INVESTMENT HOLDING CORPORATION 2001-01-16 US claimed
US-12031065-B2 Adhesive composition comprising a polyurethane and a cationic dopant E INK CORPORATION (US) 2024-07-09 US disclosed
US-11827816-B2 Adhesive composition comprising a polyurethane and a cationic dopant E INK CORPORATION (US) 2023-11-28 US disclosed
US-20230102482-A1 ADHESIVE COMPOSITION COMPRISING A POLYURETHANE AND A CATIONIC DOPANT E INK CORPORATION 2023-03-30 US disclosed
CN-113004854-B Polyurethane adhesive layer for electro-optical assemblies 伊英克公司 2022-09-30 CN disclosed
CN-114375319-A Adhesive composition comprising polyurethane and cationic dopant 伊英克公司 2022-04-19 CN disclosed
EP-3908461-A2 FILM COATING METHOD USING ENGRAVING ROLLER SYSTEM BASF SE (DE) 2021-11-17 EP disclosed
CN-113004854-A Polyurethane adhesive layer for electro-optical assemblies 伊英克公司 2021-06-22 CN disclosed
US-20060058418-A1 Materials leading to improved dental composites and dental composites made therefrom E. I. DU PONT DE NEMOURS AND COMPANY 2006-03-16 US disclosed
US-20060058414-A1 Materials leading to improved dental composites and dental composites made therefrom E. I. DU PONT DE NEMOURS AND COMPANY 2006-03-16 US disclosed
US-20060058415-A1 Materials leading to improved dental composites and dental composites made therefrom E. I. DU PONT DE NEMOURS AND COMPANY 2006-03-16 US disclosed
US-6174956-B1 POLYURETHANES IN DISPERSANTS AND CHAIN EXTENSION NATIONAL STARCH AND CHEMICAL INVESTMENT HOLDING CORPORATION 2001-01-16 US disclosed
US-5336711-A Binder composition and its use for the production of coating or sealing compositions BAYER AKTIENGESELLSCHAFT (DE) 1994-08-09 US disclosed
US-5102774-A Carboxyl-containing polyurethanes of trimethylhexamethylene diisocyanate, dimethylolpropionic acid and an hydroxyethyl (meth)acrylate; methylene chloride solvent resistance ARMSTRONG WORLD INDUSTRIES, INC. (US) 1992-04-07 US disclosed
US-5089376-A From condensation reaction of a diisocyanate, a hydroxy alkyl acrylate, and a carboxylic acid polyol ARMSTRONG WORLD INDUSTRIES, INC. (US) 1992-02-18 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20060058415-A1 Materials leading to improved dental composites and dental composites made therefrom WASF2, CAD, THEM6 SLC22A6 1908/4885SMN1; SMN2 2211/4885MAPT 516/4885
US-20060058418-A1 Materials leading to improved dental composites and dental composites made therefrom WASF2, CAD, THEM6 SLC22A6 1908/4885SMN1; SMN2 2211/4885MAPT 516/4885
US-20060058414-A1 Materials leading to improved dental composites and dental composites made therefrom WASF2, CAD, THEM6 SLC22A6 1908/4885SMN1; SMN2 2211/4885MAPT 516/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.