Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA3 | P0DMS8 | 8/20 | 0.44 |
| ▸ | TRPV1 | Q8NER1 | 3/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | TP53 | P04637 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.36 |
| ▸ | TMIGD3 | P0DMS9 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.36 |
| ▸ | CASP1 | P29466 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.35 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | GLA | P06280 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7873250 | 0.85 | ADORA3 (0.37) | ADORA3TRPV1MAPTTP53ALDH1A1 | |
| SCHEMBL8323648 | 0.85 | ADORA3 (0.45) | ADORA3TRPV1ALDH1A1TMIGD3KDM4E | |
| SCHEMBL8330375 | 0.84 | ADORA3 (0.42) | ADORA3TRPV1 | |
| SCHEMBL8323291 | 0.82 | ADORA3 (0.43) | ADORA3TRPV1 | |
| SCHEMBL8327248 | 0.79 | ADORA3 (0.68) | ADORA3TRPV1TP53ALDH1A1TMIGD3 | |
| SCHEMBL8327956 | 0.78 | ADORA3 (0.49) | ADORA3TRPV1MAPTALDH1A1TMIGD3 | |
| SCHEMBL8325950 | 0.77 | ADORA3 (0.46) | ADORA3TRPV1MAPTTP53ALDH1A1 | |
| SCHEMBL7873236 | 0.77 | ADORA3 (0.40) | ADORA3TRPV1MAPTALDH1A1TMIGD3 | |
| SCHEMBL8327558 | 0.77 | ADORA3 (0.54) | ADORA3TRPV1MAPTTP53ALDH1A1 | |
| SCHEMBL8325990 | 0.75 | ADORA3 (0.44) | ADORA3TRPV1MAPTTP53ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0943615-A1 | 1,4-DIHYDROPYRIDINE DERIVATIVES | Nikken Chemicals Company, Limited (JP) | 1999-09-22 | — | — | EP | disclosed |