Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA3 | P0DMS8 | 6/20 | 0.54 |
| ▸ | TRPV1 | Q8NER1 | 3/20 | 0.53 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | TMIGD3 | P0DMS9 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 3/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | CASP1 | P29466 | 1/20 | 0.43 |
| ▸ | CASP7 | P55210 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8327248 | 0.88 | ADORA3 (0.68) | ADORA3TRPV1ALDH1A1TMIGD3HPGD | |
| SCHEMBL8324841 | 0.80 | ADORA3 (0.46) | ADORA3TRPV1MAPTMAPK1ALDH1A1 | |
| SCHEMBL8325950 | 0.79 | ADORA3 (0.46) | ADORA3TRPV1MAPTALDH1A1CYP3A4 | |
| SCHEMBL8330375 | 0.78 | ADORA3 (0.42) | ADORA3TRPV1 | |
| SCHEMBL8328228 | 0.77 | ADORA3 (0.44) | ADORA3TRPV1MAPTMAPK1ALDH1A1 | |
| SCHEMBL8323291 | 0.75 | ADORA3 (0.43) | ADORA3TRPV1 | |
| SCHEMBL29173860 | 0.74 | ALDH1A1 (0.71) | ADORA3TRPV1MAPTALDH1A1MEN1 | |
| SCHEMBL1665260 | 0.74 | MAPT (0.68) | ADORA3MAPTMAPK1ALDH1A1CACNA1C | |
| SCHEMBL8797106 | 0.73 | LMNA (0.49) | TRPV1MAPTALDH1A1MEN1KMT2A | |
| SCHEMBL8797103 | 0.73 | LMNA (0.51) | MAPTALDH1A1MEN1KMT2AHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0943615-A1 | 1,4-DIHYDROPYRIDINE DERIVATIVES | Nikken Chemicals Company, Limited (JP) | 1999-09-22 | — | — | EP | disclosed |