Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA3 | P0DMS8 | 12/20 | 0.68 |
| ▸ | TRPV1 | Q8NER1 | 3/20 | 0.66 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.56 |
| ▸ | TMIGD3 | P0DMS9 | 2/20 | 0.55 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | TP53 | P04637 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.49 |
| ▸ | CACNA1D | Q01668 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8327558 | 0.88 | ADORA3 (0.54) | ADORA3TRPV1ALDH1A1TMIGD3LMNA | |
| SCHEMBL8325950 | 0.81 | ADORA3 (0.46) | ADORA3TRPV1ALDH1A1TMIGD3LMNA | |
| SCHEMBL7680777 | 0.81 | ADORA3 (1.00) | ADORA3TRPV1ALDH1A1TMIGD3CACNA1D | |
| SCHEMBL8324841 | 0.81 | ADORA3 (0.46) | ADORA3TRPV1ALDH1A1TMIGD3LMNA | |
| SCHEMBL29173860 | 0.80 | ALDH1A1 (0.71) | ADORA3TRPV1ALDH1A1LMNATP53 | |
| SCHEMBL7682982 | 0.80 | ADORA3 (1.00) | ADORA3TRPV1ALDH1A1TMIGD3LMNA | |
| SCHEMBL8328228 | 0.79 | ADORA3 (0.44) | ADORA3TRPV1ALDH1A1TMIGD3LMNA | |
| SCHEMBL7687629 | 0.79 | ADORA3 (0.75) | ADORA3TRPV1ALDH1A1TMIGD3LMNA | |
| SCHEMBL7152871 | 0.78 | ALDH1A1 (0.78) | ADORA3ALDH1A1LMNATP53HPGD | |
| SCHEMBL8330375 | 0.77 | ADORA3 (0.42) | ADORA3TRPV1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0943615-A1 | 1,4-DIHYDROPYRIDINE DERIVATIVES | Nikken Chemicals Company, Limited (JP) | 1999-09-22 | — | — | EP | disclosed |