Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | DHODH | Q02127 | 5/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | NCK1 | P16333 | 1/20 | 0.40 |
| ▸ | BACE1 | P56817 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | FABP3 | P05413 | 1/20 | 0.38 |
| ▸ | FABP4 | P15090 | 1/20 | 0.38 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.37 |
| ▸ | GAA | P10253 | 2/20 | 0.37 |
| ▸ | RAB9A | P51151 | 2/20 | 0.37 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.37 |
| ▸ | ITGAV | P06756 | 1/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8323296 | 0.84 | MEN1 (0.44) | MEN1KMT2ADHODHCYP1A2ALDH1A1 | |
| SCHEMBL8328431 | 0.82 | KDM4E (0.60) | MEN1KMT2ADHODHALDH1A1KDM4E | |
| SCHEMBL8328993 | 0.73 | MEN1 (0.51) | MEN1KMT2ADHODHCYP1A2ALDH1A1 | |
| SCHEMBL23247265 | 0.72 | CYP1A2 (0.68) | MEN1KMT2ACYP1A2ALDH1A1KDM4E | |
| SCHEMBL8330122 | 0.71 | RARB (0.53) | MEN1KMT2ADHODHCYP1A2ALDH1A1 | |
| SCHEMBL6194060 | 0.70 | MEN1 (0.57) | MEN1KMT2ACYP1A2ALDH1A1KDM4E | |
| SCHEMBL8322442 | 0.69 | KDM4E (0.55) | MEN1KMT2ACYP1A2ALDH1A1KDM4E | |
| SCHEMBL11811065 | 0.67 | CYP1A2 (0.52) | MEN1KMT2ADHODHCYP1A2ALDH1A1 | |
| SCHEMBL8326990 | 0.67 | RAB9A (0.53) | MEN1KMT2ACYP1A2ALDH1A1KDM4E | |
| SCHEMBL8830006 | 0.66 | PSMB5 (0.57) | MEN1KMT2ACYP1A2ALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0709377-B1 | Process for producing quinolin-2-yl benzoic acid compounds | ASAHI GLASS CO LTD (JP) | 1999-09-29 | — | — | EP | disclosed |
| US-5780634-A | Process for producing 2-(carboxyphenyl)-4-quinolinecarboxylic acid compounds | THE GREEN CROSS CORPORATION (JP) | 1998-07-14 | — | — | US | disclosed |
| EP-0709377-A1 | Process for producing quinolin-2-yl benzoic acid compounds | ASAHI GLASS COMPANY LTD. (JP) | 1996-05-01 | — | — | EP | disclosed |