Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIP4K2C | Q8TBX8 | 8/20 | 0.46 |
| ▸ | PIP4K2A | P48426 | 5/20 | 0.46 |
| ▸ | TNNI3K | Q59H18 | 1/20 | 0.43 |
| ▸ | GSK3B | P49841 | 1/20 | 0.41 |
| ▸ | TGM2 | P21980 | 1/20 | 0.41 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25667539 | 0.84 | ENPP2 (0.54) | PIP4K2CPIP4K2AGSK3BTGM2ENPP2 | |
| SCHEMBL11882073 | 0.81 | SOS1 (0.54) | — | |
| SCHEMBL3245767 | 0.76 | MEN1 (0.58) | GSK3B | |
| SCHEMBL2877698 | 0.75 | GSK3B (0.59) | GSK3B | |
| SCHEMBL24383402 | 0.73 | ENPP2 (0.43) | PIP4K2CPIP4K2AGSK3BTGM2ENPP2 | |
| SCHEMBL5457984 | 0.73 | ENPP2 (0.43) | PIP4K2CPIP4K2ATNNI3KGSK3BTGM2 | |
| SCHEMBL4191619 | 0.73 | XDH (0.54) | PIP4K2AGSK3B | |
| SCHEMBL28324029 | 0.73 | TNNI3K (0.51) | PIP4K2CPIP4K2ATNNI3K | |
| SCHEMBL29501363 | 0.73 | TNNI3K (0.51) | PIP4K2CPIP4K2ATNNI3K | |
| SCHEMBL12656068 | 0.73 | ENPP2 (0.39) | ENPP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0640595-B1 | SUBSTITUTED TERTIARY AMINO COMPOUND OR SALT THEREOF | YAMANOUCHI PHARMA CO LTD (JP) | 1999-03-24 | — | — | EP | disclosed |
| CN-1039228-C | Novel substituted tert-amino compund | YAMANOUCHI PHARMA CO LTD (JP) | 1998-07-22 | — | — | CN | disclosed |
| US-5538976-A | ANTICARCINOGENIC AGENTS AND ENZYME INHIBITORS FOR AROMATASE | YAMANOUCHI PHARMACEUTICAL CO., LTD. (JP) | 1996-07-23 | — | — | US | disclosed |
| EP-0640595-A1 | NOVEL SUBSTITUTED TERTIARY AMINO COMPOUND OR SALT THEREOF | YAMANOUCHI PHARMACEUTICAL CO. LTD. (JP) | 1995-03-01 | — | — | EP | disclosed |
| CN-1079962-A | New substituted tertiary amine compound and salt thereof | YAMANOUCHI PHARMA CO LTD (JP) | 1993-12-29 | — | — | CN | disclosed |