Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | METAP2 | P50579 | 2/20 | 0.38 |
| ▸ | CTSS | P25774 | 1/20 | 0.32 |
| ▸ | CTSK | P43235 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | METAP1 | P53582 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | REN | P00797 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8323683 | 0.94 | METAP2 (0.39) | METAP2CTSSCTSKMETAP1REN | |
| SCHEMBL8327502 | 0.88 | METAP2 (0.39) | METAP2CTSSCTSKMEN1KMT2A | |
| SCHEMBL8329953 | 0.88 | METAP2 (0.37) | METAP2CTSSCTSKLMNA | |
| SCHEMBL8798752 | 0.85 | METAP2 (0.40) | METAP2CTSSCTSKMETAP1 | |
| SCHEMBL8328594 | 0.83 | REN (0.39) | METAP2CTSSCTSKREN | |
| SCHEMBL8800115 | 0.81 | METAP2 (0.37) | METAP2CTSSCTSK | |
| SCHEMBL8332090 | 0.80 | METAP2 (0.38) | METAP2CTSSCTSKMEN1KMT2A | |
| SCHEMBL8800052 | 0.80 | METAP2 (0.38) | METAP2METAP1 | |
| SCHEMBL8798548 | 0.79 | METAP2 (0.34) | METAP2 | |
| SCHEMBL8329946 | 0.78 | EPHX1 (0.49) | METAP2CTSSCTSKMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5908863-A | ANTIGROWTH AGENT FOR BONES | DOMPE' S.P.A. (IT) | 1999-06-01 | — | — | US | disclosed |
| EP-0792878-A2 | Geminal carboxylic acids and esters thereof, pharmaceutical formulations containing them useful in the treatment of bone dysmetabolism | Dompé S.P.A. (IT) | 1997-09-03 | — | — | EP | disclosed |