Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.67 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.61 |
| ▸ | POLB | P06746 | 1/20 | 0.61 |
| ▸ | GAA | P10253 | 1/20 | 0.61 |
| ▸ | HTT | P42858 | 1/20 | 0.60 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.57 |
| ▸ | MEN1 | O00255 | 1/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.57 |
| ▸ | MAOA | P21397 | 1/20 | 0.55 |
| ▸ | MAOB | P27338 | 1/20 | 0.55 |
| ▸ | LMNA | P02545 | 3/20 | 0.54 |
| ▸ | ATM | Q13315 | 1/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23501044 | 0.92 | MAPT (0.56) | MAPTALDH1A1POLBGAAHTT | |
| SCHEMBL7815093 | 0.88 | MAPT (0.58) | MAPTALDH1A1POLBGAAHTT | |
| SCHEMBL11076598 | 0.88 | MAPT (0.58) | MAPTALDH1A1POLBGAAHTT | |
| SCHEMBL11075907 | 0.88 | MAPT (0.58) | MAPTALDH1A1POLBGAAHTT | |
| SCHEMBL8326524 | 0.87 | ALDH1A1 (0.59) | MAPTALDH1A1POLBGAAKDM4E | |
| SCHEMBL8323528 | 0.87 | ALDH1A1 (0.59) | MAPTALDH1A1POLBGAAKDM4E | |
| Hydrochloric Acid SCHEMBL11076058 | 0.86 | MAPT (0.57) | MAPTALDH1A1POLBGAAHTT | |
| SCHEMBL14198699 | 0.83 | MAPT (0.67) | MAPTPOLBHTTCYP2D6KDM4E | |
| SCHEMBL9739025 | 0.80 | HTR1A (0.56) | MAPT | |
| SCHEMBL16884151 | 0.79 | GAA (0.63) | ALDH1A1GAAKDM4EMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0760368-B1 | PYRIMIDINE DERIVATIVES | NISSHIN FLOUR MILLING CO (JP) | 1999-07-28 | — | — | EP | disclosed |
| US-5736550-A | TREATMENT OF GASTROINTESTINAL TRACT DISORDERS | NISSHIN FLOUR MILLING CO., LTD. (JP) | 1998-04-07 | — | — | US | disclosed |
| EP-0760368-A1 | NOVEL PYRIMIDINE DERIVATIVE | NISSHIN FLOUR MILLING CO., LTD. (JP) | 1997-03-05 | — | — | EP | disclosed |