Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.56 |
| ▸ | LMNA | P02545 | 2/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.54 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.53 |
| ▸ | POLB | P06746 | 1/20 | 0.53 |
| ▸ | GAA | P10253 | 1/20 | 0.53 |
| ▸ | ACHE | P22303 | 2/20 | 0.52 |
| ▸ | BACE1 | P56817 | 1/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
| ▸ | BCHE | P06276 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8329181 | 0.92 | MAPT (0.67) | MAPTLMNAL3MBTL1ALDH1A1POLB | |
| SCHEMBL9739025 | 0.87 | HTR1A (0.56) | MAPTSIGMAR1 | |
| SCHEMBL23501067 | 0.85 | MEN1 (0.58) | MAPTSIGMAR1ALDH1A1POLBACHE | |
| SCHEMBL23501029 | 0.82 | SIGMAR1 (0.57) | MAPTSIGMAR1ACHEBACE1KDM4E | |
| SCHEMBL7815093 | 0.80 | MAPT (0.58) | MAPTSIGMAR1ALDH1A1POLBGAA | |
| SCHEMBL11075907 | 0.80 | MAPT (0.58) | MAPTSIGMAR1ALDH1A1POLBGAA | |
| SCHEMBL11076598 | 0.80 | MAPT (0.58) | MAPTSIGMAR1ALDH1A1POLBGAA | |
| SCHEMBL7292460 | 0.80 | BCHE (0.56) | LMNAL3MBTL1SIGMAR1ALDH1A1ACHE | |
| SCHEMBL8326524 | 0.79 | ALDH1A1 (0.59) | MAPTLMNASIGMAR1ALDH1A1POLB | |
| SCHEMBL8323528 | 0.79 | ALDH1A1 (0.59) | MAPTLMNASIGMAR1ALDH1A1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021115413-A1 | NEUROMUSCULAR-BLOCKING DRUG AND PREPARATION METHOD THEREFOR | 江苏恒瑞医药股份有限公司 | 2021-06-17 | — | — | WO | disclosed |
| WO-2021115413-A1 | NEUROMUSCULAR-BLOCKING DRUG AND PREPARATION METHOD THEREFOR | 江苏恒瑞医药股份有限公司 | 2021-06-17 | — | — | WO | disclosed |