Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.59 |
| ▸ | POLB | P06746 | 1/20 | 0.59 |
| ▸ | GAA | P10253 | 1/20 | 0.59 |
| ▸ | MAOA | P21397 | 1/20 | 0.55 |
| ▸ | MAOB | P27338 | 1/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.54 |
| ▸ | MEN1 | O00255 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.54 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | ATM | Q13315 | 1/20 | 0.52 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
| ▸ | PDE2A | O00408 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7809212 | 0.88 | GAA (0.51) | ALDH1A1POLBGAAKDM4EMEN1 | |
| SCHEMBL11073388 | 0.88 | GAA (0.51) | ALDH1A1POLBGAAKDM4EMEN1 | |
| SCHEMBL11071315 | 0.88 | GAA (0.51) | ALDH1A1POLBGAAKDM4EMEN1 | |
| SCHEMBL8329181 | 0.87 | MAPT (0.67) | ALDH1A1POLBGAAMAOAMAOB | |
| SCHEMBL8326524 | 0.87 | ALDH1A1 (0.59) | ALDH1A1POLBGAAMAOAMAOB | |
| Hydrochloric Acid SCHEMBL11079512 | 0.86 | GAA (0.52) | ALDH1A1GAAKDM4EMEN1KMT2A | |
| SCHEMBL9208591 | 0.84 | SIGMAR1 (0.52) | GAAMEN1KMT2ASIGMAR1 | |
| SCHEMBL23501044 | 0.79 | MAPT (0.56) | ALDH1A1POLBGAAKDM4EMEN1 | |
| SCHEMBL16884151 | 0.79 | GAA (0.63) | ALDH1A1GAAKDM4EMEN1KMT2A | |
| SCHEMBL8327679 | 0.79 | ALDH1A1 (0.53) | ALDH1A1POLBGAAMAOAMAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0760368-B1 | PYRIMIDINE DERIVATIVES | NISSHIN FLOUR MILLING CO (JP) | 1999-07-28 | — | — | EP | disclosed |
| US-5736550-A | TREATMENT OF GASTROINTESTINAL TRACT DISORDERS | NISSHIN FLOUR MILLING CO., LTD. (JP) | 1998-04-07 | — | — | US | disclosed |
| EP-0760368-A1 | NOVEL PYRIMIDINE DERIVATIVE | NISSHIN FLOUR MILLING CO., LTD. (JP) | 1997-03-05 | — | — | EP | disclosed |