Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RARA | P10276 | 11/20 | 0.44 |
| ▸ | RARB | P10826 | 11/20 | 0.44 |
| ▸ | RARG | P13631 | 11/20 | 0.44 |
| ▸ | DHODH | Q02127 | 2/20 | 0.35 |
| ▸ | GPR35 | Q9HC97 | 2/20 | 0.34 |
| ▸ | PRKAB2 | O43741 | 1/20 | 0.32 |
| ▸ | PRKAG1 | P54619 | 1/20 | 0.32 |
| ▸ | PRKAA2 | P54646 | 1/20 | 0.32 |
| ▸ | PRKAA1 | Q13131 | 1/20 | 0.32 |
| ▸ | PRKAG3 | Q9UGI9 | 1/20 | 0.32 |
| ▸ | PRKAG2 | Q9UGJ0 | 1/20 | 0.32 |
| ▸ | PRKAB1 | Q9Y478 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | MMP2 | P08253 | 1/20 | 0.32 |
| ▸ | MMP9 | P14780 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8335170 | 0.87 | RARB (0.44) | RARARARBRARGNPC1RAB9A | |
| SCHEMBL6593233 | 0.85 | RARA (0.60) | RARARARBRARG | |
| SCHEMBL8329424 | 0.81 | RARA (0.42) | RARARARBRARGMMP2MMP9 | |
| SCHEMBL6592317 | 0.78 | RARA (0.56) | RARARARBRARG | |
| SCHEMBL8329425 | 0.77 | RARA (0.41) | RARARARBRARGDHODHGPR35 | |
| SCHEMBL6590162 | 0.77 | RARA (0.46) | RARARARBRARGNPC1RAB9A | |
| SCHEMBL6592120 | 0.75 | RARA (0.52) | RARARARBRARG | |
| SCHEMBL6593231 | 0.74 | RARA (0.67) | RARARARBRARG | |
| SCHEMBL6592227 | 0.73 | RARB (0.46) | RARARARBRARGRAB9A | |
| SCHEMBL8328655 | 0.73 | RARB (0.52) | RARARARBRARGNPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5958954-A | 2,2-DIALKYL-4-ARYL-SUBSTITUTED BENZOPYRAN AND BENZOTHIOPYRAN DERIVATIVES | ALLERGAN SALES, INC. (US) | 1999-09-28 | — | — | US | disclosed |