Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RARA | P10276 | 10/20 | 0.42 |
| ▸ | RARB | P10826 | 10/20 | 0.42 |
| ▸ | RARG | P13631 | 10/20 | 0.42 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.36 |
| ▸ | OPRD1 | P41143 | 3/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.34 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.32 |
| ▸ | MMP2 | P08253 | 1/20 | 0.32 |
| ▸ | MMP9 | P14780 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | PPARG | P37231 | 1/20 | 0.31 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8335174 | 0.87 | RARB (0.42) | RARARARBRARGPTPN1OPRD1 | |
| SCHEMBL6593233 | 0.83 | RARA (0.60) | RARARARBRARG | |
| SCHEMBL6590162 | 0.82 | RARA (0.46) | RARARARBRARGMAPTLMNA | |
| SCHEMBL8329422 | 0.81 | RARA (0.44) | RARARARBRARGMMP2MMP9 | |
| SCHEMBL6589881 | 0.76 | RARA (0.45) | RARARARBRARGPTPN1MAPT | |
| SCHEMBL6592317 | 0.75 | RARA (0.56) | RARARARBRARGOPRD1 | |
| SCHEMBL8328656 | 0.72 | RARB (0.48) | RARARARBRARG | |
| SCHEMBL6593231 | 0.72 | RARA (0.67) | RARARARBRARG | |
| SCHEMBL6596504 | 0.71 | RARA (0.60) | RARARARBRARG | |
| SCHEMBL24727736 | 0.71 | RARA (0.52) | RARARARBRARGOPRD1KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5958954-A | 2,2-DIALKYL-4-ARYL-SUBSTITUTED BENZOPYRAN AND BENZOTHIOPYRAN DERIVATIVES | ALLERGAN SALES, INC. (US) | 1999-09-28 | — | — | US | disclosed |