Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RARB | P10826 | 17/20 | 0.52 |
| ▸ | RARA | P10276 | 16/20 | 0.52 |
| ▸ | RARG | P13631 | 16/20 | 0.52 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | HNF4A | P41235 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5480486 | 0.85 | RARB (0.73) | RARBRARARARG | |
| SCHEMBL6240904 | 0.84 | RARB (0.71) | RARBRARARARG | |
| SCHEMBL6397552 | 0.84 | RARB (0.51) | RARBRARARARG | |
| SCHEMBL8328656 | 0.80 | RARB (0.48) | RARBRARARARGNPC1RAB9A | |
| SCHEMBL8772792 | 0.79 | RARB (0.61) | RARBRARARARG | |
| SCHEMBL6234600 | 0.75 | RARA (0.53) | RARBRARARARG | |
| SCHEMBL8329422 | 0.73 | RARA (0.44) | RARBRARARARGNPC1RAB9A | |
| SCHEMBL8335170 | 0.73 | RARB (0.44) | RARBRARARARGNPC1RAB9A | |
| SCHEMBL8580705 | 0.72 | RARB (0.65) | RARBRARARARGNPC1RAB9A | |
| SCHEMBL8772626 | 0.72 | RARA (0.62) | RARBRARARARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5958954-A | 2,2-DIALKYL-4-ARYL-SUBSTITUTED BENZOPYRAN AND BENZOTHIOPYRAN DERIVATIVES | ALLERGAN SALES, INC. (US) | 1999-09-28 | — | — | US | disclosed |
| US-5952345-A | RETINOID ACID RECEPTOR ANTAGONIST; A DERIVATIVES OF ARYL-SUBSTITUTED AND ARYL (3-OXO-1-PROPENLY)-SUBSTITUTED BENZOPYRAN, BENZOTHIOPYRAN, 1,2-DIHYDROQUINOLINE; PREVENTING TOXICITY OR SIDE EFFECTS CAUSED BY RETINOIDS OR VITAMIN A | ALLERGAN SALES, INC. (US) | 1999-09-14 | — | — | US | disclosed |
| US-5877207-A | SKIN DISORDERS; ANTICARCINOGENIC AGENTS | ALLERGAN SALES, INC. (US) | 1999-03-02 | — | — | US | disclosed |