Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 2/20 | 0.42 |
| ▸ | MAOB | P27338 | 2/20 | 0.42 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | KDM1A | O60341 | 1/20 | 0.39 |
| ▸ | CYP19A1 | P11511 | 9/20 | 0.39 |
| ▸ | NR1D1 | P20393 | 1/20 | 0.39 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.39 |
| ▸ | CNR1 | P21554 | 1/20 | 0.37 |
| ▸ | CNR2 | P34972 | 1/20 | 0.37 |
| ▸ | CYP11B1 | P15538 | 2/20 | 0.37 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.37 |
| ▸ | CRHBP | P24387 | 1/20 | 0.36 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8328066 | 0.93 | CYP19A1 (0.44) | POLBCYP19A1CYP11B1CYP11B2CRHBP | |
| SCHEMBL8325528 | 0.86 | CYP19A1 (0.53) | MAOAMAOBPOLBCYP19A1CYP11B1 | |
| SCHEMBL8323103 | 0.86 | ESR1 (0.49) | MAOAMAOBKDM1ACYP19A1NR1D1 | |
| SCHEMBL8326433 | 0.86 | CYP19A1 (0.39) | POLBCYP19A1CYP11B1CYP11B2CRHBP | |
| SCHEMBL8324221 | 0.86 | AR (0.45) | MAOAMAOBPOLBKDM1ACYP19A1 | |
| SCHEMBL8322680 | 0.85 | CYP19A1 (0.45) | CYP19A1 | |
| SCHEMBL8327043 | 0.83 | CYP19A1 (0.45) | KDM1ACYP19A1NR1D1NR1H3 | |
| SCHEMBL8324619 | 0.81 | KCNJ1 (0.46) | POLBCYP19A1CRHBPCRHR2 | |
| SCHEMBL8323517 | 0.81 | KCNJ1 (0.46) | POLBCYP19A1CRHBPCRHR2 | |
| SCHEMBL8329024 | 0.80 | CYP19A1 (0.39) | POLBCYP19A1CYP11B1CYP11B2CRHBP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0640595-B1 | SUBSTITUTED TERTIARY AMINO COMPOUND OR SALT THEREOF | YAMANOUCHI PHARMA CO LTD (JP) | 1999-03-24 | — | — | EP | disclosed |
| US-5538976-A | ANTICARCINOGENIC AGENTS AND ENZYME INHIBITORS FOR AROMATASE | YAMANOUCHI PHARMACEUTICAL CO., LTD. (JP) | 1996-07-23 | — | — | US | disclosed |
| EP-0640595-A1 | NOVEL SUBSTITUTED TERTIARY AMINO COMPOUND OR SALT THEREOF | YAMANOUCHI PHARMACEUTICAL CO. LTD. (JP) | 1995-03-01 | — | — | EP | disclosed |