Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EDNRA | P25101 | 9/20 | 0.42 |
| ▸ | EDNRB | P24530 | 8/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | TRIP13 | Q15645 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 2/20 | 0.33 |
| ▸ | TP53 | P04637 | 2/20 | 0.33 |
| ▸ | RAB9A | P51151 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6580603 | 0.93 | EDNRA (0.47) | EDNRAEDNRBSMN1; SMN2ALDH1A1KDM4E | |
| SCHEMBL6580607 | 0.87 | EDNRA (0.42) | EDNRAEDNRBSMN1; SMN2ALDH1A1KDM4E | |
| SCHEMBL8326733 | 0.85 | EDNRA (0.38) | EDNRAEDNRBSMN1; SMN2ALDH1A1KDM4E | |
| SCHEMBL8435290 | 0.78 | EDNRA (0.47) | EDNRAEDNRBSMN1; SMN2ALDH1A1KDM4E | |
| SCHEMBL8433247 | 0.77 | BRS3 (0.39) | EDNRASMN1; SMN2ALDH1A1KDM4EHPGD | |
| SCHEMBL8524654 | 0.77 | SMN1; SMN2 (0.39) | EDNRASMN1; SMN2ALDH1A1KDM4EHPGD | |
| SCHEMBL7498870 | 0.77 | EDNRA (0.59) | EDNRAEDNRBSMN1; SMN2ALDH1A1KDM4E | |
| SCHEMBL8435288 | 0.77 | EDNRA (0.48) | EDNRAEDNRBSMN1; SMN2ALDH1A1KDM4E | |
| SCHEMBL8329557 | 0.74 | MEN1 (0.39) | EDNRAEDNRBSMN1; SMN2ALDH1A1KDM4E | |
| SCHEMBL8329904 | 0.74 | PPARG (0.38) | EDNRAEDNRBSMN1; SMN2ALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5856509-A | HYPOTENSIVE AGENTS | ROUSSEL UCLAF (FR) | 1999-01-05 | — | — | US | disclosed |