Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR3 | P51677 | 8/20 | 0.46 |
| ▸ | DRD4 | P21917 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 3/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | ROCK2 | O75116 | 2/20 | 0.41 |
| ▸ | PDE2A | O00408 | 1/20 | 0.40 |
| ▸ | CCR2 | P41597 | 1/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8622390 | 0.90 | LTA4H (0.44) | POLBKMT2AMEN1 | |
| SCHEMBL8617203 | 0.87 | POLB (0.48) | CCR3POLBKMT2AMEN1 | |
| SCHEMBL8624170 | 0.85 | ALDH1A1 (0.43) | POLBPDE2AKMT2AMEN1 | |
| SCHEMBL8622621 | 0.85 | KMT2A (0.52) | POLBKMT2AMEN1 | |
| SCHEMBL8617330 | 0.85 | ALDH1A1 (0.54) | POLBPDE2AKMT2AMEN1 | |
| SCHEMBL8617097 | 0.83 | KMT2A (0.49) | POLBKMT2AMEN1 | |
| SCHEMBL8618019 | 0.82 | DRD4 (0.52) | CCR3DRD4 | |
| SCHEMBL8329547 | 0.77 | CCR3 (0.47) | CCR3DRD4POLBSMN1; SMN2ROCK2 | |
| SCHEMBL8329545 | 0.77 | CCR3 (0.53) | CCR3DRD4POLBSMN1; SMN2CCR2 | |
| SCHEMBL8622104 | 0.74 | SLC6A4 (0.44) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5753654-A | GASTROINTESTINAL DISORDERS | NISSHIN FLOUR MILLING CO., LTD. (JP) | 1998-05-19 | — | — | US | disclosed |
| US-5736550-A | TREATMENT OF GASTROINTESTINAL TRACT DISORDERS | NISSHIN FLOUR MILLING CO., LTD. (JP) | 1998-04-07 | — | — | US | disclosed |